TY - JOUR T1 - EFFECTS OF AMPHETAMINE, CHLORPROMAZINE, PENTOBARBITAL, AND ETHANOL ON OPERANT RESPONSE DURATION JF - Journal of Pharmacology and Experimental Therapeutics JO - J Pharmacol Exp Ther SP - 17 LP - 23 VL - 144 IS - 1 AU - Bernard Weiss AU - Victor G. Laties Y1 - 1964/04/01 UR - http://jpet.aspetjournals.org/content/144/1/17.abstract N2 - Dogs were trained to press against a response button with their noses. Whenever a dog accumulated 1 minute of nose-pressing, a food reinforcement was delivered. No restriction was placed on the number of individual responses needed to accumulate the 1-minute total. Amphetamine, pentobarbital, and ethanol all produced increases in the number of responses per reinforcement as dose was increased. Chlorpromazine had no effect up to a dose that caused the dogs to sleep. Combinations of amphetamine and ethanol, or amphetamine and pentobarbital produced substantial increases in the effects observed with the individual doses. The Williams & Wilkins Company ER -