@article {Welty110, author = {J. D. Welty and W. O. Read}, title = {STUDIES ON SOME CARDIAC EFFECTS OF TAURINE}, volume = {144}, number = {1}, pages = {110--115}, year = {1964}, publisher = {American Society for Pharmacology and Experimental Therapeutics}, abstract = {Experiments were performed to determine the effect of taurine on the intracellular potassium of heart tissue. The data show that: (1) taurine, in the presence of 10-6 M epinephrine or 1.25 x 10-6 M digoxin, promotes cellular accumulation of potassium in heart slices and abolishes or reverses the loss of cell potassium when heart slices are incubated in the presence of 10-4 M epinephrine or 1.25 x 10-4 M digoxin; (2) epinephnine, digoxin and procaine amide increase the conversion of taunine to isethionic acid by heart slices, quinidine has no effect, while acetylcholine depresses the conversion; (3) taurine, in the intact dog heart, prevents the efflux of potassium which accompanies lange doses of epinephrine. The Williams \& Wilkins Company}, issn = {0022-3565}, URL = {https://jpet.aspetjournals.org/content/144/1/110}, eprint = {https://jpet.aspetjournals.org/content/144/1/110.full.pdf}, journal = {Journal of Pharmacology and Experimental Therapeutics} }