TY - JOUR T1 - THE METABOLIC FATE OF CARISOPRODOL IN THE DOG JF - Journal of Pharmacology and Experimental Therapeutics JO - J Pharmacol Exp Ther SP - 21 LP - 27 VL - 138 IS - 1 AU - J. F. Douglas AU - B. J. Ludwig AU - A. Schlosser Y1 - 1962/10/01 UR - http://jpet.aspetjournals.org/content/138/1/21.abstract N2 - In the dog, carisoprodol is largely metabolized to a compound tentatively identified as hydroxycarisoprodol. Hydroxymeprobamate and small quantities of meprobamate also occur in the urine. Carisoprodol itself is excreted unchanged in trace amounts. After intravenous administration of carisoprodol to dogs, the major circulating carbamate is the unchanged drug. Hydroxycarisoprodol, hydroxymeprobamate and meprobamate are also present in the blood. ER -