RT Journal Article
SR Electronic
T1 THE METABOLIC FATE OF CARISOPRODOL IN THE DOG
JF Journal of Pharmacology and Experimental Therapeutics
JO J Pharmacol Exp Ther
FD American Society for Pharmacology and Experimental Therapeutics
SP 21
OP 27
VO 138
IS 1
A1 J. F. Douglas
A1 B. J. Ludwig
A1 A. Schlosser
YR 1962
UL http://jpet.aspetjournals.org/content/138/1/21.abstract
AB In the dog, carisoprodol is largely metabolized to a compound tentatively identified as hydroxycarisoprodol. Hydroxymeprobamate and small quantities of meprobamate also occur in the urine. Carisoprodol itself is excreted unchanged in trace amounts. After intravenous administration of carisoprodol to dogs, the major circulating carbamate is the unchanged drug. Hydroxycarisoprodol, hydroxymeprobamate and meprobamate are also present in the blood.