RT Journal Article
SR Electronic
T1 SEROTONIN-LIKE CARDIORESPIRATORY EFFECTS OF A SEROTONIX ANTAGONIST
JF Journal of Pharmacology and Experimental Therapeutics
JO J Pharmacol Exp Ther
FD American Society for Pharmacology and Experimental Therapeutics
SP 47
OP 52
VO 134
IS 1
A1 D. F. J. Halmagyi
A1 H. J. H. Colebatch
YR 1961
UL http://jpet.aspetjournals.org/content/134/1/47.abstract
AB The administration of 0.5 mg/kg 1-methyl-D-lysergic acid butanolamide (Deseril, Sandoz) in 9 sheep resulted in an increase in pulmonary arterial pressure and resistance, a rise in the mean non-elastic resistance of the lungs and a fall in lung compliance. These changes were found to be similar to those obtained during the continuous infusion of serotonin in 2 sheep.