PT - JOURNAL ARTICLE AU - Aldunate, Jorge AU - Goldstein, Leonide TI - QUANTITATIVE ELECTROENCEPHALOGRAPHIC STUDIES ON THE EFFECTS OF MORPHINE AND NALORPHINE ON RABBIT BRAIN DP - 1960 Oct 01 TA - Journal of Pharmacology and Experimental Therapeutics PG - 204--211 VI - 130 IP - 2 4099 - http://jpet.aspetjournals.org/content/130/2/204.short 4100 - http://jpet.aspetjournals.org/content/130/2/204.full SO - J Pharmacol Exp Ther1960 Oct 01; 130 AB - Quantitative electroencephalographic studies have been done on the effects of morphine and nalorphine on brain electrogenesis in rabbits. It has been found that the curves relating log-dose/effect are not the same for the effects of these drugs. The blocking action of nalorphine on morphine revealed an apparent all-or-none threshold of action and a proportionally longer duration of action for small doses of nalorphine than for large doses.