PT - JOURNAL ARTICLE AU - Marie-Jeanne Laroche AU - Bernard B. Brodie TI - LACK OF RELATIONSHIP BETWEEN INHIBITION OF MONOAMINE OXIDASE AND POTENTIATION OF HEXOBARBITAL HYPNOSIS DP - 1960 Oct 01 TA - Journal of Pharmacology and Experimental Therapeutics PG - 134--137 VI - 130 IP - 2 4099 - http://jpet.aspetjournals.org/content/130/2/134.short 4100 - http://jpet.aspetjournals.org/content/130/2/134.full SO - J Pharmacol Exp Ther1960 Oct 01; 130 AB - A number of compounds inhibit monoamine oxidase and prolong the duration of hexobarbital hypnosis. The two effects are due to different mechanisms. The effect on hexobarbital hypnosis is relatively short-lasting and results from inhibition of the metabolizing enzyme in liver microsomes; the effect on MAO is long-lasting.