PT  - JOURNAL ARTICLE
AU  - Donald T. Walz
AU  - Gertrude D. Maengwyn-Davies
TI  - THE MECHANISM OF ISOPROTERENOL VASOMOTOR REVERSAL BY PHENYLEPHRINE
DP  - 1960 Jun 01
TA  - Journal of Pharmacology and Experimental Therapeutics
PG  - 208--213
VI  - 129
IP  - 2
4099  - http://jpet.aspetjournals.org/content/129/2/208.short
4100  - http://jpet.aspetjournals.org/content/129/2/208.full
SO  - J Pharmacol Exp Ther1960 Jun 01; 129
AB  - Isoproterenol vasomotor reversal by phenylephrine occurred in spinal dogs, adrenalectomized dogs, and in debuffered dogs. The isoproterenol responses were modified in dogs in which the heart was replaced by a mechanical pump. The heart may contribute to the reversal observed in intact dogs. However, isoproterenol reversal can be demonstrated to cause increases in the peripheral resistance and contractions of the nictitating membrane.