TY - JOUR T1 - ANALGESIC POTENCY OF NORMORPHINE IN PATIENTS WITH POSTOPERATIVE PAIN JF - Journal of Pharmacology and Experimental Therapeutics JO - J Pharmacol Exp Ther SP - 260 LP - 263 VL - 124 IS - 3 AU - LOUIS LASAGNA AU - THOMAS J. De KORNFELD Y1 - 1958/11/01 UR - http://jpet.aspetjournals.org/content/124/3/260.abstract N2 - A controlled clinical comparison of morphine and normorphine in 60 patients suffering from postoperative pain is reported. Normorphine was found to be approximately one-fourth as active as morphine. It appears unlikely that N-demethylation of morphine is necessary for the analgesic effect of morphine in man. © 1958, by The Williams & Wilkins Company ER -