@article {Tedeschi161, author = {Avid H. Tedeschi and Ewart A. Swinyari}, title = {EFFECTS OF ANTICONVULSANT DRUGS ON RECOVERY TIME FROM TONIC-CLONIC SEIZURES IN MICE AND RATS}, volume = {124}, number = {2}, pages = {161--164}, year = {1958}, publisher = {American Society for Pharmacology and Experimental Therapeutics}, abstract = {Seven clinically useful anticonvulsant drugs were tested for their effects on maximal electroshock seizure (MES) pattern and recovery time from maximal (tonic-clonic) seizures. The doses tested in rats were approximate ED20{\textquoteright}s by the MES test; those tested in mice were approximate ED5{\textquoteright}s by this same test. Since only minor changes in maximal seizure pattern were produced by the doses of drugs employed, recovery time from maximal seizures was measured. All of the compounds tested significantly prolonged recovery time. The significance of these results is discussed.}, issn = {0022-3565}, URL = {https://jpet.aspetjournals.org/content/124/2/161}, eprint = {https://jpet.aspetjournals.org/content/124/2/161.full.pdf}, journal = {Journal of Pharmacology and Experimental Therapeutics} }