RT Journal Article
SR Electronic
T1 EFFECTS OF SCOPOLAMINE AND ATROPINE ON ELECTROENCEPH-ALOGRAPHIC AND BEHAVIORAL REACTIONS DUE TO HYPOTHALAMIC STIMULATION
JF Journal of Pharmacology and Experimental Therapeutics
JO J Pharmacol Exp Ther
FD American Society for Pharmacology and Experimental Therapeutics
SP 198
OP 208
VO 116
IS 2
A1 V. C. Longo
YR 1956
UL http://jpet.aspetjournals.org/content/116/2/198.abstract
AB A study was made of the actions of scopolamine and atropine on cerebral electrical (electroencephalogram) activity and on the neurovegetative and behavioral reactions provoked by stimulation of the hypothalamus in the rabbit. The two alkaloids markedly influence the electroencephalographic tracing and the electroencephalògraphic activation pattern obtained by stimulation of some subcortical centers with scopolamine exerting its action in doses [unknown] to [unknown] that of atropine. Both alkaloids proved to be without action on the neurovegetative and behavioral response which follows hypothalamic stimulation. The relation of these results to the anticholinergic action exerted by the drugs at the level of the central nervous system is discussed.