RT Journal Article SR Electronic T1 SEROTONIN AS A MEDIATOR OF RESERPINE ACTION IN BRAIN JF Journal of Pharmacology and Experimental Therapeutics JO J Pharmacol Exp Ther FD American Society for Pharmacology and Experimental Therapeutics SP 84 OP 89 VO 116 IS 1 A1 Pletscher, Alfred A1 Shore, Parkhurst A. A1 Brodie, Bernard B. YR 1956 UL http://jpet.aspetjournals.org/content/116/1/84.abstract AB The administration of reserpine to rabbits in doses as low as 0.1 mgm. per kgm. releases serotonin in brain. This observation supports the view that serotonin has a role in brain function and that the central action of reserpine is mediated through liberation of serotonin.