RT Journal Article SR Electronic T1 Use of a Physiologically Based Pharmacokinetic Model to Study the Time to Reach Brain Equilibrium: An Experimental Analysis of the Role of Blood-Brain Barrier Permeability, Plasma Protein Binding, and Brain Tissue Binding JF Journal of Pharmacology and Experimental Therapeutics JO J Pharmacol Exp Ther FD American Society for Pharmacology and Experimental Therapeutics DO 10.1124/jpet.104.079319 A1 Xingrong Liu A1 Bill J Smith A1 Cuiping Chen A1 Ernesto Callegari A1 Stacey L Becker A1 Xi Chen A1 Julie Cianfrogna A1 Angela C Doran A1 Shawn D Doran A1 John P Gibbs A1 Natilie Hosea A1 Jianhua Liu A1 Frederick R Nelson A1 Mark A Szewc A1 Jeffery Van Deusen YR 2005 UL http://jpet.aspetjournals.org/content/early/2005/03/02/jpet.104.079319.abstract AB