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OtherInflammation, Immunopharmacology, and Asthma

CANNABIDIOL ENHANCES INTESTINAL CB2 RECEPTOR EXPRESSION AND ACTIVATION INCREASING REGULATORY T CELLS AND REDUCES MURINE ACUTE GRAFT-VERSUS-HOST DISEASE WITHOUT INTERFERING WITH THE GRAFT-VERSUS-LEUKEMIA RESPONSE

Bárbara Betônico Berg, Jaqueline Silva Soares, Isabela Ribeiro Paiva, Barbara Maximino Rezende, Milene Alvarenga Rachid, Stêfany Bruno de Assis Cau, Thiago Roberto Lima Romero, Vanessa Pinho, Mauro Martins Teixeira and Marina Gomes Miranda Castor
Journal of Pharmacology and Experimental Therapeutics March 3, 2021, JPET-AR-2020-000479; DOI: https://doi.org/10.1124/jpet.120.000479
Bárbara Betônico Berg
1Pharmacology, UFMG, Brazil
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Jaqueline Silva Soares
2Pharmacology, ICB/UFMG, Brazil
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Isabela Ribeiro Paiva
2Pharmacology, ICB/UFMG, Brazil
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Barbara Maximino Rezende
3UFMG, Brazil
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Milene Alvarenga Rachid
2Pharmacology, ICB/UFMG, Brazil
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Stêfany Bruno de Assis Cau
2Pharmacology, ICB/UFMG, Brazil
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Thiago Roberto Lima Romero
2Pharmacology, ICB/UFMG, Brazil
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Vanessa Pinho
2Pharmacology, ICB/UFMG, Brazil
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Mauro Martins Teixeira
2Pharmacology, ICB/UFMG, Brazil
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Marina Gomes Miranda Castor
2Pharmacology, ICB/UFMG, Brazil
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  • For correspondence: marinacastor@gmail.com

Data Supplement

  • Supplemental Figures -

    Supplemental Figure 1. Antibodies used in immunofluorescence.

    Supplemental Figure 2. Flow cytometry analysis of spleen.

    Supplemental Figure 3. Flow cytometry analysis of small intestine.

    Supplemental Figure 4. Flow cytometry analysis of liver.

    Supplemental Figure 5. Immunofluorescence of CD4/CB2 in small intestine.

    Supplemental Figure 6. Immunofluorescence of FoxP3/CB2 in small intestine.

    Supplemental Figure 7. Immunofluorescence of CD8/CB2 in small intestine.

    Supplemental Figure 8. Intravital analysis after GVHD was induced in Balb/c mice using C57BL/6J GFP+ mice as donors.

  View article

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