Research ArticleDrug Discovery and Translational Medicine
Using Chimeric Mice with Humanized Livers to Predict Human Drug Metabolism and a Drug-Drug Interaction
Toshihiko Nishimura, Yajing Hu, Manhong Wu, Edward Pham, Hiroshi Suemizu, Menashe Elazar, Michael Liu, Ramazan Idilman, Cihan Yurdaydin, Peter Angus, Catherine Stedman, Brian Murphy, Jeffrey Glenn, Masato Nakamura, Tatsuji Nomura, Yuan Chen, Ming Zheng, William L. Fitch and Gary Peltz
Journal of Pharmacology and Experimental Therapeutics November 8, 2012, jpet.112.198697; DOI: https://doi.org/10.1124/jpet.112.198697
Toshihiko Nishimura
1 Stanford University;
Yajing Hu
1 Stanford University;
Manhong Wu
1 Stanford University;
Edward Pham
1 Stanford University;
Hiroshi Suemizu
2 Central Institute for Experimental Animals;
Menashe Elazar
1 Stanford University;
Michael Liu
1 Stanford University;
Ramazan Idilman
3 University of Ankara;
Cihan Yurdaydin
3 University of Ankara;
Peter Angus
4 University of Melbourne;
Catherine Stedman
5 ChristChurch Hospital;
Brian Murphy
6 Eiger Biosciences;
Jeffrey Glenn
1 Stanford University;
Masato Nakamura
2 Central Institute for Experimental Animals;
Tatsuji Nomura
2 Central Institute for Experimental Animals;
Yuan Chen
7 Genentech;
Ming Zheng
1 Stanford University;
William L. Fitch
1 Stanford University;
Gary Peltz
8 Stanford University School of Medicine
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