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Journal of Pharmacology and Experimental Therapeutics

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Latest Articles

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    Impact of SLC43A3/ENBT1 Expression and Function on 6-Mercaptopurine Transport and Cytotoxicity in Human Acute Lymphoblastic Leukemia Cells
    Nicholas M. Ruel, Khanh Hoa Nguyen, Chan S. Kim, Laura P.S. Andrade and James R. Hammond
    Journal of Pharmacology and Experimental Therapeutics September 2022, 382 (3) 335-345; DOI: https://doi.org/10.1124/jpet.122.001155
  • Open Access
    Preclinical Characterization of LY3209590, a Novel Weekly Basal Insulin Fc-Fusion Protein
    Julie S. Moyers, Ryan J. Hansen, Jonathan W. Day, Craig D. Dickinson, Chen Zhang, Xiaoping Ruan, Liyun Ding, Robin M. Brown, Hana E. Baker and John M. Beals
    Journal of Pharmacology and Experimental Therapeutics September 2022, 382 (3) 346-355; DOI: https://doi.org/10.1124/jpet.122.001105
  • Open Access
    Influence of Glutathione-S-Transferase A1*B Allele on the Metabolism of the Aromatase Inhibitor, Exemestane, in Human Liver Cytosols and in Patients Treated With Exemestane
    Irina Teslenko, Julia Trudeau, Shaman Luo, Christy J.W. Watson, Gang Chen, Cristina I. Truica and Philip Lazarus
    Journal of Pharmacology and Experimental Therapeutics September 2022, 382 (3) 327-334; DOI: https://doi.org/10.1124/jpet.122.001232
  • Intratracheal Administration of Acyl Coenzyme A Acyltransferase-1 Inhibitor K-604 Reduces Pulmonary Inflammation Following Bleomycin-Induced Lung Injury
    Open Access
    Intratracheal Administration of Acyl Coenzyme A Acyltransferase-1 Inhibitor K-604 Reduces Pulmonary Inflammation Following Bleomycin-Induced Lung Injury
    Emily R. Stevenson, Melissa L. Wilkinson, Elena Abramova, Changjiang Guo and Andrew J. Gow
    Journal of Pharmacology and Experimental Therapeutics September 2022, 382 (3) 356-365; DOI: https://doi.org/10.1124/jpet.122.001284
  • You have access
    Peripheral Administration of Selective Glycine Transporter-2 Inhibitor, Oleoyl-D-Lysine, Reverses Chronic Neuropathic Pain but Not Acute or Inflammatory Pain in Male Mice
    Bruce S. Wilson, Julian Peiser-Oliver, Alexander Gillis, Sally Evans, Claudia Alamein, Shannon N. Mostyn, Susan Shimmon, Tristan Rawling, MacDonald J. Christie, Robert J. Vandenberg and Sarasa A. Mohammadi
    Journal of Pharmacology and Experimental Therapeutics September 2022, 382 (3) 246-255; DOI: https://doi.org/10.1124/jpet.122.001265
  • You have access
    Effect of Novel Biotherapeutic Elevating Angiopoietin 1 on Progression of Diabetic Nephropathy in Diabetic/Obese Mice
    Peng Sun, Christina S. Bartlett, Chao Zheng, Tammy Bigwarfe, Joshuaine M. Grant, Margit MacDougall, Valentina Berger, Steven Kerr, Hu Sheng Qian, Mark McHugh, Hongxing Chen, Xiaomei Zhang, Miranda L. Carpenter, Heather N. Robinson, John Miglietta, Thorsten Lamla and Ryan M. Fryer
    Journal of Pharmacology and Experimental Therapeutics September 2022, 382 (3) 266-276; DOI: https://doi.org/10.1124/jpet.121.001067
  • Open Access
    Tralesinidase Alfa Enzyme Replacement Therapy Prevents Disease Manifestations in a Canine Model of Mucopolysaccharidosis Type IIIB
    N. Matthew Ellinwood, Bethann N. Valentine, Andrew S. Hess, Jackie K. Jens, Elizabeth M. Snella, Maryam Jamil, Shannon J. Hostetter, Nicholas D. Jeffery, Jodi D. Smith, Suzanne T. Millman, Rebecca L. Parsons, Mark T. Butt, Sundeep Chandra, Martin T. Egeland, Ana B. Assis, Hemanth R. Nelvagal, Jonathan D. Cooper, Igor Nestrasil, Bryon A. Mueller, Rene Labounek, Amy Paulson, Heather Prill, Xiao Ying Liu, Huiyu Zhou, Roger Lawrence, Brett E. Crawford, Anita Grover, Ganesh Cherala, Andrew C. Melton, Anu Cherukuri, Brian R. Vuillemenot, Jill C.M. Wait, Charles A. O’Neill, Jason Pinkstaff, Joseph Kovalchin, Eric Zanelli and Emma McCullagh
    Journal of Pharmacology and Experimental Therapeutics September 2022, 382 (3) 277-286; DOI: https://doi.org/10.1124/jpet.122.001119
  • You have access
    Pharmacological Evaluation of a Pegylated Urocortin-1 Peptide in Experimental Autoimmune Disease Models
    Josef G. Heuer, Catalina M. Meyer, Hana E. Baker, Andrea Geiser, Jonathan Lucchesi, Daniel Xu, Matthew Hamang, Jennifer A. Martin, Charlie Hu, Kenneth D. Roth, Kannan Thirunavukkarasu, Jorge Alsina-Fernandez and Yanfei L. Ma
    Journal of Pharmacology and Experimental Therapeutics September 2022, 382 (3) 287-298; DOI: https://doi.org/10.1124/jpet.122.001151
  • You have access
    Influence of CYP2B6 Pharmacogenetics on Stereoselective Inhibition and Induction of Bupropion Metabolism by Efavirenz in Healthy Volunteers
    Brandon T. Gufford, Ingrid F. Metzger, Nadia O. Bamfo, Eric A. Benson, Andrea R. Masters, Jessica Bo Li Lu and Zeruesenay Desta
    Journal of Pharmacology and Experimental Therapeutics September 2022, 382 (3) 313-326; DOI: https://doi.org/10.1124/jpet.122.001277
  • Open Access
    Antinociceptive and Analgesic Effects of (2R,6R)-Hydroxynorketamine
    Jonathan G. Yost, Hildegard A. Wulf, Caroline A. Browne and Irwin Lucki
    Journal of Pharmacology and Experimental Therapeutics September 2022, 382 (3) 256-265; DOI: https://doi.org/10.1124/jpet.122.001278

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