Latest Articles

Article Type

You have access
Puerarin Ameliorates 5-Fluorouracil–Induced Intestinal Mucositis in Mice by Inhibiting JAKs
Liang Wang, Baohui Song, Yan Hu, Jun Chen, Shuaishuai Zhang, Dapeng Chen and Jingyu Wang

Journal of Pharmacology and Experimental Therapeutics November 2021, 379 (2) 147-155; DOI: https://doi.org/10.1124/jpet.121.000677
You have access
Streptococcal Exotoxin Streptolysin O Causes Vascular Endothelial Dysfunction Through PKCβ Activation
Masashi Mukohda, Sho Nakamura, Kosuke Takeya, Akira Matsuda, Takanori Yano, Mihiro Seki, Risuke Mizuno and Hiroshi Ozaki

Journal of Pharmacology and Experimental Therapeutics November 2021, 379 (2) 117-124; DOI: https://doi.org/10.1124/jpet.121.000752
You have access
Minimal Physiologically Based Pharmacokinetic-Pharmacodynamic (mPBPK-PD) Model of N-Acetylgalactosamine–Conjugated Small Interfering RNA Disposition and Gene Silencing in Preclinical Species and Humans
Vivaswath S. Ayyar, Dawei Song, Songmao Zheng, Thomas Carpenter and Donald L. Heald

Journal of Pharmacology and Experimental Therapeutics November 2021, 379 (2) 134-146; DOI: https://doi.org/10.1124/jpet.121.000805
You have access
Define Mesenchymal Stem Cell from Its Fate: Biodisposition of Human Mesenchymal Stem Cells in Normal and Concanavalin A–Induced Liver Injury Mice
Li Han, Chenhui Ma, Huige Peng, Zhitao Wu, Huiming Xu, Jiajun Wu, Ning Zhang, Qinghui Jiang, Chen Ma, Ruimin Huang, Hai Li and Guoyu Pan

Journal of Pharmacology and Experimental Therapeutics November 2021, 379 (2) 125-133; DOI: https://doi.org/10.1124/jpet.121.000607
You have access
A Retinoic Acid Receptor β₂ Agonist Improves Cardiac Function in a Heart Failure Model
Xiao-Han Tang, Jessica Gambardella, Stanislovas Jankauskas, Xujun Wang, Gaetano Santulli, Lorraine J. Gudas and Roberto Levi

Journal of Pharmacology and Experimental Therapeutics November 2021, 379 (2) 182-190; DOI: https://doi.org/10.1124/jpet.121.000806
You have access
Semimechanistic Modeling of the Effects of Blast Overpressure Exposure on Cefazolin Pharmacokinetics in Mice
Daniel J. Selig, Geoffrey C. Chin, Alexander G. Bobrov, Jesse P. DeLuca, Derese Getnet, Jeffrey R. Livezey, Joseph B. Long, Venkatasivasai S. Sajja, Brett E. Swierczewski, Stuart D. Tyner and Vlado Antonic

Journal of Pharmacology and Experimental Therapeutics November 2021, 379 (2) 175-181; DOI: https://doi.org/10.1124/jpet.121.000797
You have access
Identification and Characterization of Two Structurally Related Dipeptides that Enhance Catalytic Efficiency of Neurolysin
Srinidhi Jayaraman, Joanna Kocot, Shiva Hadi Esfahani, Naomi J. Wangler, Arzu Uyar, Yehia Mechref, Paul C. Trippier, Thomas J. Abbruscato, Alex Dickson, Hideki Aihara, David A. Ostrov and Vardan T. Karamyan

Journal of Pharmacology and Experimental Therapeutics November 2021, 379 (2) 191-202; DOI: https://doi.org/10.1124/jpet.121.000840
You have access
Cationic Compounds with SARS-CoV-2 Antiviral Activity and Their Interaction with Organic Cation Transporter/Multidrug and Toxin Extruder Secretory Transporters
Lucy Martinez-Guerrero, Xiaohong Zhang, Kimberley M. Zorn, Sean Ekins and Stephen H. Wright

Journal of Pharmacology and Experimental Therapeutics October 2021, 379 (1) 96-107; DOI: https://doi.org/10.1124/jpet.121.000619
Open Access
Preclinical Evaluation of the Effects of Trazpiroben (TAK-906), a Novel, Potent Dopamine D₂/D₃ Receptor Antagonist for the Management of Gastroparesis
Roger L. Whiting, Agnes Choppin, Gary Luehr and Jeffrey R. Jasper

Journal of Pharmacology and Experimental Therapeutics October 2021, 379 (1) 85-95; DOI: https://doi.org/10.1124/jpet.121.000698
You have access
Protein Kinase N Family Negatively Regulates Constitutive Androstane Receptor-Mediated Transcriptional Induction of Cytochrome P450 2b10 in the Livers of Mice
Atsushi Kawase, Hideyuki Mukai, Shunsuke Tateishi, Shintaro Kuroda, Akira Kazaoka, Ryosuke Satoh, Hiroaki Shimada, Reiko Sugiura and Masahiro Iwaki

Journal of Pharmacology and Experimental Therapeutics October 2021, 379 (1) 53-63; DOI: https://doi.org/10.1124/jpet.121.000790

Main menu

User menu

Search

Latest Articles

Pages

Navigate

More Information

ASPET's Other Journals