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Journal of Pharmacology and Experimental Therapeutics

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Latest Articles

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    Methamphetamine Dysregulation of the Central Nervous System and Peripheral Immunity
    Douglas R. Miller, Mengfei Bu, Adithya Gopinath, Luis R. Martinez and Habibeh Khoshbouei
    Journal of Pharmacology and Experimental Therapeutics December 2021, 379 (3) 372-385; DOI: https://doi.org/10.1124/jpet.121.000767
  • You have access
    5-Aza-4′-thio-2′-deoxycytidine, a New Orally Bioavailable Nontoxic “Best-in-Class”: DNA Methyltransferase 1–Depleting Agent in Clinical Development
    William B. Parker and Jaideep V. Thottassery
    Journal of Pharmacology and Experimental Therapeutics November 2021, 379 (3) 211-222; DOI: https://doi.org/10.1124/jpet.121.000758
  • You have access
    Therapeutic Effects of Time-Limited Treatment with Brivaracetam on Posttraumatic Epilepsy after Fluid Percussion Injury in the Rat
    Clifford L. Eastman, Jason S. Fender, Pavel Klein and Raimondo D’Ambrosio
    Journal of Pharmacology and Experimental Therapeutics December 2021, 379 (3) 310-323; DOI: https://doi.org/10.1124/jpet.121.000585
  • Modulation of Oxidative Phosphorylation with IM156 Attenuates Mitochondrial Metabolic Reprogramming and Inhibits Pulmonary Fibrosis
    Open Access
    Modulation of Oxidative Phosphorylation with IM156 Attenuates Mitochondrial Metabolic Reprogramming and Inhibits Pulmonary Fibrosis
    Robert N. Willette, Parth Mangrolia, Stephen M. Pondell, Christopher Young Woo Lee, Sanghee Yoo, Marc S. Rudoltz, Benjamin R. Cowen and Dean J. Welsch
    Journal of Pharmacology and Experimental Therapeutics November 2021, 379 (3) 290-300; DOI: https://doi.org/10.1124/jpet.121.000811
  • Open Access
    Deconstructing the Pharmacological Contribution of Sphingosine-1 Phosphate Receptors to Mouse Models of Multiple Sclerosis Using the Species Selectivity of Ozanimod, a Dual Modulator of Human Sphingosine 1-Phosphate Receptor Subtypes 1 and 5
    Julie V. Selkirk, Kevin C. Dines, Yingzhuo Grace Yan, Nathan Ching, Deepak Dalvie, Shameek Biswas, Andrea Bortolato, Jeffrey M. Schkeryantz, Carlos Lopez, Iliana Ruiz and Richard Hargreaves
    Journal of Pharmacology and Experimental Therapeutics December 2021, 379 (3) 386-399; DOI: https://doi.org/10.1124/jpet.121.000741
  • Differential Susceptibilities of Catecholamines to Metabolism by Monoamine Oxidases
    You have access
    Differential Susceptibilities of Catecholamines to Metabolism by Monoamine Oxidases
    David S. Goldstein, Genessis Castillo, Patti Sullivan and Yehonatan Sharabi
    Journal of Pharmacology and Experimental Therapeutics November 2021, 379 (3) 253-259; DOI: https://doi.org/10.1124/jpet.121.000826
  • Open Access
    Pharmacokinetics and Pharmacodynamic Effects of Nemvaleukin Alfa, a Selective Agonist of the Intermediate-Affinity IL-2 Receptor, in Cynomolgus Monkeys
    Jared E. Lopes, Lei Sun, Heather L. Flick, Erin A. Murphy and Heather C. Losey
    Journal of Pharmacology and Experimental Therapeutics November 2021, 379 (2) 203-210; DOI: https://doi.org/10.1124/jpet.121.000612
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    A Chemoproteomics Approach to Determine the Mechanism of Testicular Toxicity for the Bruton’s Tyrosine Kinase Inhibitor CC-292
    Matt Labenski, Lukas Voortman, Aravind Prasad Medikonda, Philip J. Sherratt and Alan F. Corin
    Journal of Pharmacology and Experimental Therapeutics November 2021, 379 (2) 166-174; DOI: https://doi.org/10.1124/jpet.121.000614
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    Resolvin Conjugates in Tissue Regeneration 1 Promote Alveolar Fluid Clearance by Activating Alveolar Epithelial Sodium Channels and Na, K-ATPase in Lipopolysaccharide-Induced Acute Lung Injury
    Qian Yang, Hao-ran Xu, Shu-yang Xiang, Chen Zhang, Yang Ye, Chen-xi Shen, Hong-xia Mei, Pu-hong Zhang, Hong-yu Ma, Sheng-xing Zheng, Fang-gao Smith, Sheng-wei Jin and Qian Wang
    Journal of Pharmacology and Experimental Therapeutics November 2021, 379 (2) 156-165; DOI: https://doi.org/10.1124/jpet.121.000712
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    Puerarin Ameliorates 5-Fluorouracil–Induced Intestinal Mucositis in Mice by Inhibiting JAKs
    Liang Wang, Baohui Song, Yan Hu, Jun Chen, Shuaishuai Zhang, Dapeng Chen and Jingyu Wang
    Journal of Pharmacology and Experimental Therapeutics November 2021, 379 (2) 147-155; DOI: https://doi.org/10.1124/jpet.121.000677

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ISSN 1521-0103 (Online)

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