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Streptococcal Exotoxin Streptolysin O Causes Vascular Endothelial Dysfunction Through PKCβ Activation
Masashi Mukohda, Sho Nakamura, Kosuke Takeya, Akira Matsuda, Takanori Yano, Mihiro Seki, Risuke Mizuno and Hiroshi Ozaki

Journal of Pharmacology and Experimental Therapeutics August 13, 2021, JPET-AR-2021-000752; DOI: https://doi.org/10.1124/jpet.121.000752
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Define mesenchymal stem cell from its fate:Biodisposition of human mesenchymal stem cells in normal and Con-A induced liver injury mice
Li Han, Chenhui Ma, Huige Peng, Zhitao Wu, Huiming Xu, Jiajun Wu, Ning Zhang, Qinghui Jiang, Chen Ma, Ruimin Huang, Hai Li and Guoyu Pan

Journal of Pharmacology and Experimental Therapeutics August 10, 2021, JPET-AR-2021-000607; DOI: https://doi.org/10.1124/jpet.121.000607
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A chemoproteomics approach to determine the mechanism of testicular toxicity for the Bruton's tyrosine kinase inhibitor CC-292
Matt Labenski, Lukas Voortman, Aravind Prasad Medikonda, Philip John Sherratt and Alan F Corin

Journal of Pharmacology and Experimental Therapeutics August 9, 2021, JPET-AR-2021-000614; DOI: https://doi.org/10.1124/jpet.121.000614
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Pharmacokinetics and Pharmacodynamic Effects of Nemvaleukin Alfa, a Selective Agonist of the Intermediate-Affinity IL-2 Receptor, in Cynomolgus Monkeys
Jared E. Lopes, Lei Sun, Heather L Flick, Erin A Murphy and Heather C Losey

Journal of Pharmacology and Experimental Therapeutics August 6, 2021, JPET-AR-2021-000612; DOI: https://doi.org/10.1124/jpet.121.000612
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γ-Hydroxybutyric Acid–Ethanol Drug-Drug Interaction: Reversal of Toxicity with Monocarboxylate Transporter 1 Inhibitors
Vivian Rodriguez-Cruz and Marilyn E. Morris

Journal of Pharmacology and Experimental Therapeutics July 2021, 378 (1) 42-50; DOI: https://doi.org/10.1124/jpet.121.000566
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Rosuvastatin Inhibits the Apoptosis of Platelet-Derived Growth Factor–Stimulated Vascular Smooth Muscle Cells by Inhibiting p38 via Autophagy
Jun-Hwan Jo, Hyun-Soo Park, Do-Hyung Lee, Joo-Hui Han, Kyung-Sun Heo and Chang-Seon Myung

Journal of Pharmacology and Experimental Therapeutics July 2021, 378 (1) 10-19; DOI: https://doi.org/10.1124/jpet.121.000539
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TPN672: A Novel Serotonin-Dopamine Receptor Modulator for the Treatment of Schizophrenia
Yu Wang, Yang He, Feipu Yang, Melkamu Alemu Abame, Chunhui Wu, Yanmin Peng, Linyin Feng, Jingshan Shen, Zhen Wang and Ling He

Journal of Pharmacology and Experimental Therapeutics July 2021, 378 (1) 20-30; DOI: https://doi.org/10.1124/jpet.120.000414
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The Caveolin-1 Scaffolding Domain Peptide Reverses Aging-Associated Deleterious Changes in Multiple Organs
Dhandapani Kuppuswamy, Panneerselvam Chinnakkannu, Charles Reese and Stanley Hoffman

Journal of Pharmacology and Experimental Therapeutics July 2021, 378 (1) 1-9; DOI: https://doi.org/10.1124/jpet.120.000424
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A p97/Valosin-Containing Protein Inhibitor Drug CB-5083 Has a Potent but Reversible Off-Target Effect on Phosphodiesterase-6
Henri Leinonen, Cheng Cheng, Marja Pitkänen, Christopher L. Sander, Jianye Zhang, Sama Saeid, Teemu Turunen, Alyaa Shmara, Lan Weiss, Lac Ta, Timothy Ton, Ari Koskelainen, Jesse D. Vargas, Virginia Kimonis and Krzysztof Palczewski

Journal of Pharmacology and Experimental Therapeutics July 2021, 378 (1) 31-41; DOI: https://doi.org/10.1124/jpet.120.000486
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Ginsenoside Ro Ameliorates High-Fat Diet–Induced Obesity and Insulin Resistance in Mice via Activation of the G Protein–Coupled Bile Acid Receptor 5 Pathway
Lin-shan Jiang, Wei Li, Tong-xi Zhuang, Jie-jing Yu, Shuai Sun, Zheng-cai Ju, Zheng-tao Wang, Li-li Ding and Li Yang

Journal of Pharmacology and Experimental Therapeutics June 2021, 377 (3) 441-451; DOI: https://doi.org/10.1124/jpet.120.000435

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