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Plasma and Liver Pharmacokinetics of the N-Acetylgalactosamine Short Interfering RNA JNJ-73763989 in Recombinant Adeno-Associated–Hepatitis B Virus–Infected Mice
Louis Sandra, Huybrecht T’jollyn, Nele Goeyvaerts, An Vermeulen, Anne-Gaëlle Dosne and Juan-Jose Perez-Ruixo

Journal of Pharmacology and Experimental Therapeutics October 2022, 383 (1) 70-79; DOI: https://doi.org/10.1124/jpet.122.001229
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Central Nervous System Distribution of the Ataxia-Telangiectasia Mutated Kinase Inhibitor AZD1390: Implications for the Treatment of Brain Tumors
Surabhi Talele, Wenjuan Zhang, Jiajia Chen, Shiv K. Gupta, Danielle M. Burgenske, Jann N. Sarkaria and William F. Elmquist

Journal of Pharmacology and Experimental Therapeutics October 2022, 383 (1) 91-102; DOI: https://doi.org/10.1124/jpet.122.001230
Open Access
Assessment of Inhaled Treprostinil Palmitil, Inhaled and Intravenous Treprostinil, and Oral Selexipag in a Sugen/Hypoxia Rat Model of Pulmonary Arterial Hypertension
Michel R. Corboz, Adam J. Plaunt, Vladimir S. Malinin, Zhili Li, Helena Gauani, Donald Chun, David Cipolla, Walter R. Perkins and Richard W. Chapman

Journal of Pharmacology and Experimental Therapeutics October 2022, 383 (1) 103-116; DOI: https://doi.org/10.1124/jpet.122.001174
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“Viewpoints”: New Article Category
Beverley Greenwood-Van Meerveld

Journal of Pharmacology and Experimental Therapeutics October 2022, 383 (1) 1; DOI: https://doi.org/10.1124/jpet.122.001398
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Cinnabarinic Acid Provides Hepatoprotection Against Nonalcoholic Fatty Liver Disease
Nikhil Y. Patil, Iulia Rus, Emma Downing, Ashok Mandala, Jacob E. Friedman and Aditya D. Joshi

Journal of Pharmacology and Experimental Therapeutics October 2022, 383 (1) 32-43; DOI: https://doi.org/10.1124/jpet.122.001301
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Murine Central Nervous System and Bone Marrow Distribution of the Aurora A Kinase Inhibitor Alisertib: Pharmacokinetics and Exposure at the Sites of Efficacy and Toxicity
Ju-Hee Oh, Erica A. Power, Wenjuan Zhang, David J. Daniels and William F. Elmquist

Journal of Pharmacology and Experimental Therapeutics October 2022, 383 (1) 44-55; DOI: https://doi.org/10.1124/jpet.122.001268
Open Access
Preclinical Characterization of Vadadustat (AKB-6548), an Oral Small Molecule Hypoxia-Inducible Factor Prolyl-4-Hydroxylase Inhibitor, for the Potential Treatment of Renal Anemia
Anna Zuk, Zhihai Si, Sally Loi, Santhosh Bommegowda, Debie Hoivik, Sanjay Danthi, Gyongyi Molnar, Vilmos Csizmadia and Michael Rabinowitz

Journal of Pharmacology and Experimental Therapeutics October 2022, 383 (1) 11-24; DOI: https://doi.org/10.1124/jpet.122.001126
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N-Stearoylethanolamine Inhibits Integrin-Mediated Activation, Aggregation, and Adhesion of Human Platelets
Iehor A. Hudz, Volodymyr O. Chernyshenko, Ludmila O. Kasatkina, Lesia P. Urvant, Vitaliy M. Klimashevskyi, Oksana S. Tkachenko, Halyna V. Kosiakova, Nadiia M. Hula and Tetyana M. Platonova

Journal of Pharmacology and Experimental Therapeutics October 2022, 383 (1) 2-10; DOI: https://doi.org/10.1124/jpet.122.001084
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Modulation of Ligand-Gated Glycine Receptors Via Functional Monoclonal Antibodies
Jeffrey R. Simard, Klaus Michelsen, Yan Wang, Chunhua Yang, Beth Youngblood, Barbara Grubinska, Kristin Taborn, Daniel J. Gillie, Kevin Cook, Kyu Chung, Alexander M. Long, Brian E. Hall, Paul L. Shaffer, Robert S. Foti and Jacinthe Gingras

Journal of Pharmacology and Experimental Therapeutics October 2022, 383 (1) 56-69; DOI: https://doi.org/10.1124/jpet.121.001026
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Sodium-Glucose Cotransporter-2 Inhibition Exacerbates Hepatic Encephalopathy in Biliary Cirrhotic Rats
Shao-Jung Hsu, Hui-Chun Huang, Chon Kit Pun, Ching-Chih Chang, Chiao-Lin Chuang, Yi-Hsiang Huang, Ming-Chih Hou and Fa-Yauh Lee

Journal of Pharmacology and Experimental Therapeutics October 2022, 383 (1) 25-31; DOI: https://doi.org/10.1124/jpet.122.001289

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