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Journal of Pharmacology and Experimental Therapeutics

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Latest Articles

  • Botulinum Toxin A, a Better Choice for Skeletal Muscle Block in a Comparative Study With Lidocaine in Rats
    Open Access
    Botulinum Toxin A, a Better Choice for Skeletal Muscle Block in a Comparative Study With Lidocaine in Rats
    Ke Xu, Zhan Zhang, Yueying Li, Lili Song, Jin Gou, Chengkuan Sun, Jiayang Li, Shuang Du, Rangjuan Cao and Shusen Cui
    Journal of Pharmacology and Experimental Therapeutics December 2022, 383 (3) 227-237; DOI: https://doi.org/10.1124/jpet.122.001313
  • You have access
    A Physiologically-Based Pharmacokinetic Model of the Brain Considering Regional Lipid Variance
    Andrew McPherson Heitman, Robert R. Bies and Sorell L. Schwartz
    Journal of Pharmacology and Experimental Therapeutics December 2022, 383 (3) 217-226; DOI: https://doi.org/10.1124/jpet.122.001256
  • You have access
    Pharmacodynamic and Antitumor Activity of BI 836880, a Dual VEGF and Angiopoietin 2 Inhibitor, Alone and Combined with Programmed Cell Death Protein-1 Inhibition
    Irmgard Hofmann, Anke Baum, Marco H. Hofmann, Francesca Trapani, Claudia Reichel-Voda, Diane Ehrensperger, Martin Aichinger, Florian Ebner, Nicole Budano, Norbert Schweifer, Martina Sykora, Erik Depla, Joachim Boucneau, Andreas Gschwind, Norbert Kraut, Frank Hilberg and Klaus-Peter Künkele
    Journal of Pharmacology and Experimental Therapeutics October 14, 2022, JPET-AR-2022-001255; DOI: https://doi.org/10.1124/jpet.122.001255
  • You have access
    Activation of GPR183 by 7α,25-Dihydroxycholesterol Induces Behavioral Hypersensitivity through Mitogen-Activated Protein Kinase and Nuclear Factor-κB
    Kathryn Braden, Michela Campolo, Ying Li, Zhoumou Chen, Timothy M. Doyle, Luigino Antonio Giancotti, Emanuela Esposito, Jinsong Zhang, Salvatore Cuzzocrea, Christopher Kent Arnatt and Daniela Salvemini
    Journal of Pharmacology and Experimental Therapeutics November 2022, 383 (2) 172-181; DOI: https://doi.org/10.1124/jpet.122.001283
  • You have access
    Metabotropic Glutamate Receptors Modulate Exocytotic Tau Release and Propagation
    Francesca Mazzo, Ioana Butnaru, Olivera Grubisha, Elena Ficulle, Helen Sanger, Griffin Fitzgerald, Feng Pan, Francesca Pasqui, Tracey Murray, James Monn, Xia Li, Michael Hutton, Suchira Bose, Giampietro Schiavo and Emanuele Sher
    Journal of Pharmacology and Experimental Therapeutics November 2022, 383 (2) 117-128; DOI: https://doi.org/10.1124/jpet.122.001307
  • You have access
    Differential Activation and Desensitization States Promoted by Noncanonical α7 Nicotinic Acetylcholine Receptor Agonists
    Clare Stokes, Gisela Andrea Camacho-Hernandez, Ganesh A. Thakur, Xiaoxuan Wu, Palmer Taylor and Roger L. Papke
    Journal of Pharmacology and Experimental Therapeutics November 2022, 383 (2) 157-171; DOI: https://doi.org/10.1124/jpet.122.001354
  • A Novel Truncated Liver Enriched Antimicrobial Peptide-2 Palmitoylated at its N-Terminal Antagonizes Effects of Ghrelin
    You have access
    A Novel Truncated Liver Enriched Antimicrobial Peptide-2 Palmitoylated at its N-Terminal Antagonizes Effects of Ghrelin
    Lucie Holá, Blanka Železná, Alena Karnošová, Jaroslav Kuneš, Jean-Alain Fehrentz, Séverine Denoyelle, Sonia Cantel, Miroslava Blechová, David Sýkora, Aneta Myšková and Lenka Maletínská
    Journal of Pharmacology and Experimental Therapeutics November 2022, 383 (2) 129-136; DOI: https://doi.org/10.1124/jpet.122.001322
  • Open Access
    Mitochondrial Dysfunction and Pharmacodynamics of Mitofusin Activation in Murine Charcot-Marie-Tooth Disease Type 2A
    Antonietta Franco, Xiawei Dang, Lihong Zhang, Perry B. Molinoff and Gerald W. Dorn
    Journal of Pharmacology and Experimental Therapeutics November 2022, 383 (2) 137-148; DOI: https://doi.org/10.1124/jpet.122.001332
  • You have access
    Is Diminazene an Angiotensin-Converting Enzyme 2 (ACE2) Activator? Experimental Evidence and Implications
    Shiva Hadi Esfahani, Srinidhi Jayaraman and Vardan T. Karamyan
    Journal of Pharmacology and Experimental Therapeutics November 2022, 383 (2) 149-156; DOI: https://doi.org/10.1124/jpet.122.001339
  • Open Access
    Plasma and Liver Pharmacokinetics of the N-Acetylgalactosamine Short Interfering RNA JNJ-73763989 in Recombinant Adeno-Associated–Hepatitis B Virus–Infected Mice
    Louis Sandra, Huybrecht T’jollyn, Nele Goeyvaerts, An Vermeulen, Anne-Gaëlle Dosne and Juan-Jose Perez-Ruixo
    Journal of Pharmacology and Experimental Therapeutics October 2022, 383 (1) 70-79; DOI: https://doi.org/10.1124/jpet.122.001229

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ISSN 1521-0103 (Online)

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