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The effects of dual GLP-1/GCG receptor agonists with different receptor selectivity in mouse models of obesity and NASH
Ashref Kayed, Simone Anna Melander, Suheb Khan, Kim Vietz Andreassen, Morten Asser Karsdal and Kim Henriksen

Journal of Pharmacology and Experimental Therapeutics November 23, 2022, JPET-AR-2022-001440; DOI: https://doi.org/10.1124/jpet.122.001440
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Correction to “Central Nervous System Delivery of the Catalytic Subunit of DNA-Dependent Protein Kinase Inhibitor Peposertib as Radiosensitizer for Brain Metastases”
Journal of Pharmacology and Experimental Therapeutics December 2022, 383 (3) 251; DOI: https://doi.org/10.1124/jpet.121.001069err
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Correction to “Pharmacological Comparison of Mitragynine and 7-Hydroxymitragynine: In Vitro Affinity and Efficacy for μ-Opioid Receptor and Opioid-Like Behavioral Effects in Rats”
Journal of Pharmacology and Experimental Therapeutics December 2022, 383 (3) 250; DOI: https://doi.org/10.1124/jpet.120.000189err
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Insulin Suppresses Ubiquitination via the Deubiquitinating Enzyme USP14, Independent of Proteasome Activity in H4IIEC3 Hepatocytes
Kyoko Kamoshita, Kiyo-Aki Ishii, Yumiko Tahira, Akihiro Kikuchi, Halimulati Abuduwaili, Natsumi Tajima-Shirasaki, Qifang Li, Hiroaki Takayama, Kunio Matsumoto and Toshinari Takamura

Journal of Pharmacology and Experimental Therapeutics November 15, 2022, JPET-AR-2022-001088; DOI: https://doi.org/10.1124/jpet.122.001088
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Interactive Effects of µ-Opioid and Adrenergic-α₂ Receptor Agonists in Rats: Pharmacological Investigation of the Primary Kratom Alkaloid Mitragynine and Its Metabolite 7-Hydroxymitragynine
Samuel Obeng, Francisco Leon, Avi Patel, Julio D. Zuarth Gonzalez, Lucas Chaves Da Silva, Luis F. Restrepo, Lea R. Gamez-Jimenez, Nicholas P. Ho, Maria P. Guerrero Calvache, Victoria L.C. Pallares, Justin A. Helmes, Sakura K. Shiomitsu, Paul L. Soto, Aidan J. Hampson, Christopher R. McCurdy, Lance R. McMahon, Jenny L. Wilkerson and Takato Hiranita

Journal of Pharmacology and Experimental Therapeutics December 2022, 383 (3) 182-198; DOI: https://doi.org/10.1124/jpet.122.001192
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Botulinum Toxin A, a Better Choice for Skeletal Muscle Block in a Comparative Study With Lidocaine in Rats
Ke Xu, Zhan Zhang, Yueying Li, Lili Song, Jin Gou, Chengkuan Sun, Jiayang Li, Shuang Du, Rangjuan Cao and Shusen Cui

Journal of Pharmacology and Experimental Therapeutics December 2022, 383 (3) 227-237; DOI: https://doi.org/10.1124/jpet.122.001313
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A Physiologically-Based Pharmacokinetic Model of the Brain Considering Regional Lipid Variance
Andrew McPherson Heitman, Robert R. Bies and Sorell L. Schwartz

Journal of Pharmacology and Experimental Therapeutics December 2022, 383 (3) 217-226; DOI: https://doi.org/10.1124/jpet.122.001256
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Comments on “Ocular Pharmacokinetics of Brimonidine Drug Delivery System in Monkeys and Translational Modeling for Selection of Dose and Frequency in Clinical Trials”
Eva M del Amo, Arto Urtti and Veli-Pekka Ranta

Journal of Pharmacology and Experimental Therapeutics December 2022, 383 (3) 246-247; DOI: https://doi.org/10.1124/jpet.122.001257
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Competitive Interactions Between Propofol and Diazepam: Studies in GABA_A Receptors and Zebrafish
Andrea Pence, Helen Hoyt, Megan McGrath, Stuart A. Forman and Douglas E. Raines

Journal of Pharmacology and Experimental Therapeutics December 2022, 383 (3) 238-245; DOI: https://doi.org/10.1124/jpet.122.001337
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Response to Comments on “Ocular Pharmacokinetics of Brimonidine Drug Delivery System in Monkeys and Translational Modeling for Selection of Dose and Frequency in Clinical Trials”
Mitalee Tamhane, Kenneth T. Luu and Mayssa Attar

Journal of Pharmacology and Experimental Therapeutics December 2022, 383 (3) 248-249; DOI: https://doi.org/10.1124/jpet.122.001439

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