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Journal of Pharmacology and Experimental Therapeutics

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Latest Articles

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    MDPV high-responder phenotype as a tool to evaluate candidate medications for stimulant use disorder
    Michelle R. Doyle, Lindsey N Peng, Jianjing Cao, Kenner C. Rice, Amy Hauck Newman and Gregory T. Collins
    Journal of Pharmacology and Experimental Therapeutics January 10, 2023, JPET-AR-2022-001419; DOI: https://doi.org/10.1124/jpet.122.001419
  • You have access
    Non-Coding RNAs in Clinical Practice: From Biomarkers to Therapeutic Tools
    Gaetano Santulli
    Journal of Pharmacology and Experimental Therapeutics January 2023, 384 (1) 225-226; DOI: https://doi.org/10.1124/jpet.122.001457
  • You have access
    Istaroxime and Beyond: New Therapeutic Strategies to Specifically Activate SERCA and Treat Heart Failure
    Roberta Avvisato, Stanislovas S. Jankauskas and Gaetano Santulli
    Journal of Pharmacology and Experimental Therapeutics January 2023, 384 (1) 227-230; DOI: https://doi.org/10.1124/jpet.122.001446
  • Istaroxime Metabolite PST3093 Selectively Stimulates SERCA2a and Reverses Disease-Induced Changes in Cardiac Function
    Open Access
    Istaroxime Metabolite PST3093 Selectively Stimulates SERCA2a and Reverses Disease-Induced Changes in Cardiac Function
    Martina Arici, Mara Ferrandi, Paolo Barassi, Shih-Che Hsu, Eleonora Torre, Andrea Luraghi, Carlotta Ronchi, Gwo-Jyh Chang, Francesco Peri, Patrizia Ferrari, Giuseppe Bianchi, Marcella Rocchetti and Antonio Zaza
    Journal of Pharmacology and Experimental Therapeutics January 2023, 384 (1) 231-244; DOI: https://doi.org/10.1124/jpet.122.001335
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    Attenuation of the positive-reinforcing effects of ultra-potent fentanyl analogs, along with those of fentanyl and heroin, during daily treatment with methocinnamox (MCAM) in rhesus monkeys
    Lisa R. Gerak and Charles P. France
    Journal of Pharmacology and Experimental Therapeutics December 27, 2022, JPET-AR-2022-001267; DOI: https://doi.org/10.1124/jpet.122.001267
  • You have access
    Exosomal miR-145 and miR-885 Regulate Thrombosis in COVID-19
    Jessica Gambardella, Urna Kansakar, Celestino Sardu, Vincenzo Messina, Stanislovas S. Jankauskas, Raffaele Marfella, Paolo Maggi, Xujun Wang, Pasquale Mone, Giuseppe Paolisso, Daniela Sorriento and Gaetano Santulli
    Journal of Pharmacology and Experimental Therapeutics January 2023, 384 (1) 109-115; DOI: https://doi.org/10.1124/jpet.122.001209
  • Open Access
    Identification and Characterization of ACP-5862, the Major Circulating Active Metabolite of Acalabrutinib: Both Are Potent and Selective Covalent Bruton Tyrosine Kinase Inhibitors 
    Terry Podoll, Paul G. Pearson, Allard Kaptein, Jerry Evarts, Gerjan de Bruin, Maaike Emmelot-van Hoek, Anouk de Jong, Bart van Lith, Hao Sun, Stephen Byard, Adrian Fretland, Niels Hoogenboom, Tjeerd Barf and J. Greg Slatter
    Journal of Pharmacology and Experimental Therapeutics January 2023, 384 (1) 173-186; DOI: https://doi.org/10.1124/jpet.122.001116
  • Open Access
    The Role of microRNA in the Development, Diagnosis, and Treatment of Cardiovascular Disease: Recent Developments
    Anetta Wronska
    Journal of Pharmacology and Experimental Therapeutics January 2023, 384 (1) 123-132; DOI: https://doi.org/10.1124/jpet.121.001152
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    Effects of 2,5-Dimethoxy-4-Methylamphetamine (DOM) and 2-Piperazin-1-yl-Quinoline (Quipazine) on Fentanyl Versus Food Choice in Rhesus Monkeys
    David R. Maguire
    Journal of Pharmacology and Experimental Therapeutics January 2023, 384 (1) 155-162; DOI: https://doi.org/10.1124/jpet.122.001318
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    Regulation of Ferroptosis by Non-Coding RNAs: Mechanistic Insights
    Ammad Ahmad Farooqi, Gulnara Kapanova, Sundetgali Kalmakhanov, Abay Z. Kussainov and Zaure Datkhayeva
    Journal of Pharmacology and Experimental Therapeutics January 2023, 384 (1) 20-27; DOI: https://doi.org/10.1124/jpet.121.001225

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ISSN 1521-0103 (Online)

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