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Targeting Mitochondrial Large-Conductance Calcium-Activated Potassium Channel by Hydrogen Sulfide via Heme-Binding Site
Agnieszka Walewska, Adam Szewczyk, Milena Krajewska and Piotr Koprowski

Journal of Pharmacology and Experimental Therapeutics May 2022, 381 (2) 137-150; DOI: https://doi.org/10.1124/jpet.121.001017
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Therapeutic Approaches to Nociplastic Pain Based on Findings in the Reserpine-Induced Fibromyalgia-Like Animal Model
Yukinori Nagakura

Journal of Pharmacology and Experimental Therapeutics May 2022, 381 (2) 106-119; DOI: https://doi.org/10.1124/jpet.121.001051
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Pharmacological Profiling of Antifentanyl Monoclonal Antibodies in Combination with Naloxone in Pre- and Postexposure Models of Fentanyl Toxicity
Carly A. Baehr, Mariah M. Wu, Sujata G. Pandit, Jose Arias-Umana, David AuCoin and Marco Pravetoni

Journal of Pharmacology and Experimental Therapeutics May 2022, 381 (2) 129-136; DOI: https://doi.org/10.1124/jpet.121.001048
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High Salt Upregulates Ca²⁺-Sensing Receptor Expression and Ca²⁺-Induced Relaxation of Contracted Mesenteric Arteries from Dahl Salt-Sensitive Rats
Lakeesha E. Bridges, Cicely L. Williams and Emmanuel M. Awumey

Journal of Pharmacology and Experimental Therapeutics May 2022, 381 (2) 120-128; DOI: https://doi.org/10.1124/jpet.121.001034
Open Access
Efficacy of Vesicular Monoamine Transporter 2 Inhibition and Synergy with Antipsychotics in Animal Models of Schizophrenia
Samuel R. J. Hoare, Andrea E. Kudwa, Rosa Luo and Dimitri E. Grigoriadis

Journal of Pharmacology and Experimental Therapeutics May 2022, 381 (2) 79-95; DOI: https://doi.org/10.1124/jpet.121.000979
Open Access
Resveratrol Attenuates High-Fat Diet–Induced Hepatic Lipotoxicity by Upregulating Bmi-1 Expression
Weigang Yuan, Mi Zhang, Chunxu Wang, Bin Li, Lei Li, Feng Ye and Chuanrui Xu

Journal of Pharmacology and Experimental Therapeutics May 2022, 381 (2) 96-105; DOI: https://doi.org/10.1124/jpet.121.001018
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Insulin Enhances Gene Expression of Midnolin, a Novel Genetic Risk Factor for Parkinson’s Disease, via Extracellular Signal-Regulated Kinase, Phosphoinositide 3-Kinase and Multiple Transcription Factors in SH-SY5Y Cells
Naoki Sagehashi, Yutaro Obara, Ohki Maruyama, Tadashi Nakagawa, Toru Hosoi and Kuniaki Ishii

Journal of Pharmacology and Experimental Therapeutics May 2022, 381 (2) 68-78; DOI: https://doi.org/10.1124/jpet.121.001076
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Ligustrazine attenuates liver fibrosis by targeting miR-145 mediated TGF-β/Smad signaling in an animal model of biliary atresia
Jian-Li Qiu, Guo-Feng Zhang, Yu-Na Chai, Xiao-Yan Han, Hai-Tao Zheng, Xiang-Feng Li, Fei Duan and Ling-Yan Chen

Journal of Pharmacology and Experimental Therapeutics April 9, 2022, JPET-AR-2021-001020; DOI: https://doi.org/10.1124/jpet.121.001020
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Opportunities for Precision Treatment of GRIN2A and GRIN2B Gain-of-Function Variants in Triheteromeric N-Methyl-D-Aspartate Receptors
Wei Han, Hongjie Yuan, James P. Allen, Sukhan Kim, Gil H. Shaulsky, Riley E. Perszyk, Stephen F. Traynelis and Scott J. Myers

Journal of Pharmacology and Experimental Therapeutics April 2022, 381 (1) 54-66; DOI: https://doi.org/10.1124/jpet.121.001000
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Correction to “Central Nervous System Distribution of an Opioid Agonist Combination with Synergistic Activity”
Journal of Pharmacology and Experimental Therapeutics April 2022, 381 (1) 67; DOI: https://doi.org/10.1124/jpet.121.000821err

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