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Journal of Pharmacology and Experimental Therapeutics

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Latest Articles

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    CD13 Induces Autophagy to Promote Hepatocellular Carcinoma Cell Chemoresistance Through the P38/Hsp27/CREB/ATG7 Pathway
    Yan Zhao, Huina Wu, Xiaoyan Xing, Yuqian Ma, Shengping Ji, Xinyue Xu, Xin Zhao, Sensen Wang, Wenyan Jiang, Chunyan Fang, Lei Zhang, Fang Yan and Xuejian Wang
    Journal of Pharmacology and Experimental Therapeutics September 2020, 374 (3) 512-520; DOI: https://doi.org/10.1124/jpet.120.265637
  • You have access
    Topical Application of ASN008, a Permanently Charged Sodium Channel Blocker, Shows Robust Efficacy, a Rapid Onset, and Long Duration of Action in a Mouse Model of Pruritus
    Roshni Ramachandran, Scott K. Thompson, Shelle Malkmus, Tsutomu Mieda, Jun-Hsiang Lin, Sandeep Gupta and Tony L. Yaksh
    Journal of Pharmacology and Experimental Therapeutics September 2020, 374 (3) 521-528; DOI: https://doi.org/10.1124/jpet.120.265074
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    Correction to “Biological Characterization of F508delCFTR Protein Processing by the CFTR Corrector ABBV-2222/GLPG2222”
    Journal of Pharmacology and Experimental Therapeutics September 2020, 374 (3) 499; DOI: https://doi.org/10.1124/jpet.119.261800err
  • p38<em>α</em> Regulates Expression of DUX4 in a Model of Facioscapulohumeral Muscular Dystrophy
    Open Access
    p38α Regulates Expression of DUX4 in a Model of Facioscapulohumeral Muscular Dystrophy
    L. Alejandro Rojas, Erin Valentine, Anthony Accorsi, Joseph Maglio, Ning Shen, Alan Robertson, Steven Kazmirski, Peter Rahl, Rabi Tawil, Diego Cadavid, Lorin A. Thompson, Lucienne Ronco, Aaron N. Chang, Angela M. Cacace and Owen Wallace
    Journal of Pharmacology and Experimental Therapeutics September 2020, 374 (3) 489-498; DOI: https://doi.org/10.1124/jpet.119.264689
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    Characterization of Stressed Transgenic Mice Overexpressing H2-Histamine Receptors in the Heart
    Ulrich Gergs, Uwe Kirchhefer, Fabian Bergmann, Bernhard Künstler, Natascha Mißlinger, Bastian Au, Mareen Mahnkopf, Hartmut Wache and Joachim Neumann
    Journal of Pharmacology and Experimental Therapeutics September 2020, 374 (3) 479-488; DOI: https://doi.org/10.1124/jpet.120.000063
  • Open Access
    Beneficial Effects of Soluble Guanylyl Cyclase Stimulation and Activation in Sickle Cell Disease Are Amplified by Hydroxyurea: In Vitro and In Vivo Studies
    W.A. Ferreira, H. Chweih, C. Lanaro, C.B. Almeida, P.L. Brito, E.M.F. Gotardo, L. Torres, L.I. Miguel, C.F. Franco-Penteado, F.C. Leonardo, F. Garcia, S.T.O. Saad, P.S. Frenette, D. Brockschnieder, F.F. Costa, J.P. Stasch, P. Sandner and N. Conran
    Journal of Pharmacology and Experimental Therapeutics September 2020, 374 (3) 469-478; DOI: https://doi.org/10.1124/jpet.119.264606
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    Antiemetic Effects of Cannabinoid Agonists in Nonhuman Primates
    Lisa M. Wooldridge, Lipin Ji, Yingpeng Liu, Spyros P. Nikas, Alexandros Makriyannis, Jack Bergman and Brian D. Kangas
    Journal of Pharmacology and Experimental Therapeutics September 2020, 374 (3) 462-468; DOI: https://doi.org/10.1124/jpet.120.265710
  • Therapeutic Effects of Anti-Inflammatory <em>N</em>-Acylhydrazones in the Resolution of Experimental Colitis
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    Therapeutic Effects of Anti-Inflammatory N-Acylhydrazones in the Resolution of Experimental Colitis
    Natália Cordeiro, Rosana Helena Coimbra Nogueira Freitas, Carlos Alberto Manssour Fraga and Patricia Dias Fernandes
    Journal of Pharmacology and Experimental Therapeutics September 2020, 374 (3) 420-427; DOI: https://doi.org/10.1124/jpet.120.000074
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    Renoprotective Effects of a Novel Receptor-Interacting Protein Kinase 2 Inhibitor, AS3334034, in Uninephrectomized Adriamycin-Induced Chronic Kidney Disease Rats
    Yusuke Wada, Mitsuhiro Kondo, Kumi Sakairi, Akira Nagashima, Kenichi Tokita, Hiroaki Tominaga, Hiroshi Tomiyama and Tomohisa Ishikawa
    Journal of Pharmacology and Experimental Therapeutics September 2020, 374 (3) 428-437; DOI: https://doi.org/10.1124/jpet.120.265678
  • Slow-, Tight-Binding Inhibition of CYP17A1 by Abiraterone Redefines Its Kinetic Selectivity and Dosing Regimen
    You have access
    Slow-, Tight-Binding Inhibition of CYP17A1 by Abiraterone Redefines Its Kinetic Selectivity and Dosing Regimen
    Eleanor Jing Yi Cheong, Pramod C. Nair, Rebecca Wan Yi Neo, Ho Thanh Tu, Fu Lin, Edmund Chiong, Kesavan Esuvaranathan, Hao Fan, Russell Z. Szmulewitz, Cody J. Peer, William D. Figg, Christina Li Lin Chai, John O. Miners and Eric Chun Yong Chan
    Journal of Pharmacology and Experimental Therapeutics September 2020, 374 (3) 438-451; DOI: https://doi.org/10.1124/jpet.120.265868

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