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Journal of Pharmacology and Experimental Therapeutics

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Latest Articles

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    β3-Adrenergic Receptor Agonist Prevents Diastolic Dysfunction in an Angiotensin II–Induced Cardiomyopathy Mouse Model
    Masataka Kamiya, Kuniya Asai, Yasuhiro Maejima, Akihiro Shirakabe, Koji Murai, Satsuki Noma, Hidenori Komiyama, Naoki Sato, Kyoichi Mizuno and Wataru Shimizu
    Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 473-481; DOI: https://doi.org/10.1124/jpet.120.000140
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    Correction to “Specific Lowering of Asymmetric Dimethylarginine by Pharmacological Dimethylarginine Dimethylaminohydrolase Improves Endothelial Function, Reduces Blood Pressure and Ischemia-Reperfusion Injury”
    Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 463; DOI: https://doi.org/10.1124/jpet.120.000212err
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    Phytochemical Regulation of RNA in Treating Inflammatory Bowel Disease and Colon Cancer: Inspirations from Cell and Animal Studies
    Guolin Zhang, Chi Zhang, Jia’ao Sun, Yongjian Xiong, Liang Wang and Dapeng Chen
    Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 464-472; DOI: https://doi.org/10.1124/jpet.120.000354
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    Distinct Uptake Kinetics of Alzheimer Disease Amyloid-β 40 and 42 at the Blood-Brain Barrier Endothelium
    Nidhi Sharda, Kristen M. Ahlschwede, Geoffry L. Curran, Val J. Lowe and Karunya K. Kandimalla
    Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 482-490; DOI: https://doi.org/10.1124/jpet.120.000086
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    Behavioral Battery for Testing Candidate Analgesics in Mice. II. Effects of Endocannabinoid Catabolic Enzyme Inhibitors and ∆9-Tetrahydrocannabinol
    Clare M Diester, Aron H. Lichtman and S. Stevens Negus
    Journal of Pharmacology and Experimental Therapeutics February 23, 2021, JPET-AR-2021-000497; DOI: https://doi.org/10.1124/jpet.121.000497
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    Behavioral Battery for Testing Candidate Analgesics in Mice. I. Validation with Positive and Negative Controls
    Clare M Diester, Edna J Santos, Megan Jo Moerke and S. Stevens Negus
    Journal of Pharmacology and Experimental Therapeutics February 23, 2021, JPET-AR-2020-000464; DOI: https://doi.org/10.1124/jpet.120.000464
  • Open Access
    Novel Tocolytic Strategy: Modulating Cx43 Activity by S-Nitrosation
    Scott D. Barnett, Hazik Asif, Mitchell Anderson and Iain L. O. Buxton
    Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 444-453; DOI: https://doi.org/10.1124/jpet.120.000427
  • Opening of Intermediate Conductance Ca<sup>2+</sup>-Activated K<sup>+</sup> Channels in C2C12 Skeletal Muscle Cells Increases the Myotube Diameter via the Akt/Mammalian Target of Rapamycin Pathway
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    Opening of Intermediate Conductance Ca2+-Activated K+ Channels in C2C12 Skeletal Muscle Cells Increases the Myotube Diameter via the Akt/Mammalian Target of Rapamycin Pathway
    Yuzo Iseki, Yuko Ono, Chihiro Hibi, Shoko Tanaka, Shunya Takeshita, Yuko Maejima, Junko Kurokawa, Masahiro Murakawa, Kenju Shimomura and Kazuho Sakamoto
    Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 454-462; DOI: https://doi.org/10.1124/jpet.120.000290
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    RNA Interference Targeting Liver Angiopoietin-Like Protein 3 Protects from Nephrotic Syndrome in a Rat Model Via Amelioration of Pathologic Hypertriglyceridemia
    Yitong Zhao, Masaki Goto, Nosratola D. Vaziri, Mahyar Khazaeli, Han Liu, Nazli Farahanchi, Elham Khanifar, Ted Farzaneh, Patrick A. Haslett, Hamid Moradi and Mangala M. Soundarapandian
    Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 428-435; DOI: https://doi.org/10.1124/jpet.120.000257
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    Pharmacological Comparison of Mitragynine and 7-Hydroxymitragynine: In Vitro Affinity and Efficacy for μ-Opioid Receptor and Opioid-Like Behavioral Effects in Rats
    Samuel Obeng, Jenny L. Wilkerson, Francisco León, Morgan E. Reeves, Luis F. Restrepo, Lea R. Gamez-Jimenez, Avi Patel, Anna E. Pennington, Victoria A. Taylor, Nicholas P. Ho, Tobias Braun, John D. Fortner, Morgan L. Crowley, Morgan R. Williamson, Victoria L.C. Pallares, Marco Mottinelli, Carolina Lopera-Londoño, Christopher R. McCurdy, Lance R. McMahon and Takato Hiranita
    Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 410-427; DOI: https://doi.org/10.1124/jpet.120.000189

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