Latest Articles

Article Type

You have access
Calculation of an Apical Efflux Ratio from P-Glycoprotein (P-gp) In Vitro Transport Experiments Shows an Improved Correlation with In Vivo Cerebrospinal Fluid Measurements in Rats: Impact on P-gp Screening and Compound Optimization
Holger Fischer, Claudia Senn, Mohammed Ullah, Carina Cantrill, Franz Schuler and Li Yu

Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 322-329; DOI: https://doi.org/10.1124/jpet.120.000158
You have access
Pharmacology and Mechanism of Action of HSK16149, a Selective Ligand of α2δ Subunit of Voltage-Gated Calcium Channel with Analgesic Activity in Animal Models of Chronic Pain
Xiaoli Gou, Xiaojuan Yu, Dongdong Bai, Bowei Tan, Pingfeng Cao, Meilin Qian, Xiaoxiao Zheng, Lei Chen, Zongjun Shi, Yao Li, Fei Ye, Yong Liang and Jia Ni

Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 330-337; DOI: https://doi.org/10.1124/jpet.120.000315
Open Access
Improved Inhibitory and Absorption, Distribution, Metabolism, Excretion, and Toxicology (ADMET) Properties of Blebbistatin Derivatives Indicate That Blebbistatin Scaffold Is Ideal for drug Development Targeting Myosin-2
Máté Gyimesi, Anna Á. Rauscher, Sharad Kumar Suthar, Kamirán Á. Hamow, Kinga Oravecz, István Lőrincz, Zsolt Borhegyi, Máté T. Déri, Ádám F. Kiss, Katalin Monostory, Pál Tamás Szabó, Suman Nag, Ivan Tomasic, Jacob Krans, Patrick J. Tierney, Mihály Kovács, László Kornya and András Málnási-Csizmadia

Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 358-373; DOI: https://doi.org/10.1124/jpet.120.000167
You have access
Self-Administration of Cotinine in Wistar Rats: Comparisons to Nicotine
Zheng-Ming Ding, Yong Gao, Alena M. Sentir and Xiaoying Tan

Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 338-347; DOI: https://doi.org/10.1124/jpet.120.000367
You have access
A Phenyl-Pyrrolidine Derivative Reveals a Dual Inhibition Mechanism of Myocardial Mitochondrial Permeability Transition Pore, Which Is Limited by Its Myocardial Distribution
Mathieu Panel, Abdelhakim Ahmed-Belkacem, Isaac Ruiz, Jean-François Guichou, Jean-Michel Pawlotsky, Bijan Ghaleh and Didier Morin

Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 348-357; DOI: https://doi.org/10.1124/jpet.120.000359
You have access
Pharmacological Actions of Carbamate Insecticides at Mammalian Melatonin Receptors
Grant C. Glatfelter, Anthony J. Jones, Rajendram V. Rajnarayanan and Margarita L. Dubocovich

Journal of Pharmacology and Experimental Therapeutics February 2021, 376 (2) 306-321; DOI: https://doi.org/10.1124/jpet.120.000065
You have access
Lysosomal Biogenesis and Implications for Hydroxychloroquine Disposition
Keagan P. Collins, Sandra Witta, Jonathan W. Coy, Yi Pang and Daniel L. Gustafson

Journal of Pharmacology and Experimental Therapeutics February 2021, 376 (2) 294-305; DOI: https://doi.org/10.1124/jpet.120.000309
You have access
Physiologically Based Pharmacokinetics of Lysosomotropic Chloroquine in Rat and Human
Xin Liu and William J. Jusko

Journal of Pharmacology and Experimental Therapeutics February 2021, 376 (2) 261-272; DOI: https://doi.org/10.1124/jpet.120.000385
Open Access
Activation of the G Protein–Coupled Estrogen Receptor Prevented the Development of Acute Colitis by Protecting the Crypt Cell
Qian Wang, Zhao Li, Kaixuan Liu, Jianbo Liu, Shiquan Chai, Guanyu Chen, Shuyu Wen, Tian Ming, Jiayi Wang, Yuntao Ma, Honghui Zeng, Chuanyong Liu and Bing Xue

Journal of Pharmacology and Experimental Therapeutics February 2021, 376 (2) 281-293; DOI: https://doi.org/10.1124/jpet.120.000216
Open Access
Sphingosine 1-Phosphate Receptor Modulator ONO-4641 Regulates Trafficking of T Lymphocytes and Hematopoietic Stem Cells and Alleviates Immune-Mediated Aplastic Anemia in a Mouse Model
Takaki Komiya, Masashi Gohda, Hiroki Shioya and Seishi Katsumata

Journal of Pharmacology and Experimental Therapeutics February 2021, 376 (2) 250-260; DOI: https://doi.org/10.1124/jpet.120.000277

Main menu

User menu

Search

Latest Articles

Pages

Navigate

More Information

ASPET's Other Journals