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AM833 is a novel agonist of calcitonin family G protein-coupled receptors: pharmacological comparison to six selective and non-selective agonists
Madeleine M Fletcher, Peter Keov, Tin T Truong, Grace Mennen, Caroline A Hick, Peishen Zhao, Sebastian G.B. Furness, Thomas Kruse, Trine R Clausen, Denise Wootten and Patrick M. Sexton

Journal of Pharmacology and Experimental Therapeutics March 16, 2021, JPET-AR-2021-000567; DOI: https://doi.org/10.1124/jpet.121.000567
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Acetate, a Short-Chain Fatty Acid, Acutely Lowers Heart Rate and Cardiac Contractility Along with Blood Pressure
Brian G. Poll, Jiaojiao Xu, Seungho Jun, Jason Sanchez, Nathan A. Zaidman, Xiaojun He, Laeben Lester, Dan E. Berkowitz, Nazareno Paolocci, Wei Dong Gao and Jennifer L. Pluznick

Journal of Pharmacology and Experimental Therapeutics April 2021, 377 (1) 39-50; DOI: https://doi.org/10.1124/jpet.120.000187
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Optimization of Lipophilic Metalloporphyrins Modifies Disease Outcomes in a Rat Model of Parkinsonism
Li-Ping Liang, Ruth Fulton, Erica L. Bradshaw-Pierce, Jennifer Pearson-Smith, Brian J. Day and Manisha Patel

Journal of Pharmacology and Experimental Therapeutics April 2021, 377 (1) 1-10; DOI: https://doi.org/10.1124/jpet.120.000229
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Characterization of the Onset, Progression, and Reversibility of Morphological Changes in Mouse Lung after Pharmacological Inhibition of Leucine-Rich Kinase 2 Kinase Activity
Dianne K. Bryce, Chris M. Ware, Janice D. Woodhouse, Paul J. Ciaccio, J. Michael Ellis, Laxminarayan G. Hegde, Sabu Kuruvilla, Matthew L. Maddess, Carrie G. Markgraf, Karin M. Otte, Frederique M. Poulet, Lauren M. Timmins, Matthew E. Kennedy and Matthew J. Fell

Journal of Pharmacology and Experimental Therapeutics April 2021, 377 (1) 11-19; DOI: https://doi.org/10.1124/jpet.120.000217
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Rapid Throughput Concentration-Response Analysis of Human Taste Discrimination
R. Kyle Palmer, Mariah M. Stewart and John Talley

Journal of Pharmacology and Experimental Therapeutics April 2021, 377 (1) 133-145; DOI: https://doi.org/10.1124/jpet.120.000373
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Activation of Neuronal Voltage-Gated Potassium Kv7/KCNQ/M-Current by a Novel Channel Opener SCR2682 for Alleviation of Chronic Pain
Jing Wang, Yani Liu, Fang Hu, Jiuyong Yang, Xiaoyu Guo, Xingming Hou, Chuanxia Ju and KeWei Wang

Journal of Pharmacology and Experimental Therapeutics April 2021, 377 (1) 20-28; DOI: https://doi.org/10.1124/jpet.120.000357
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Increased Interleukin-10 Expression by the Inhibition of Ca²⁺-Activated K⁺ Channel K_Ca3.1 in CD4⁺CD25⁺ Regulatory T Cells in the Recovery Phase in an Inflammatory Bowel Disease Mouse Model
Susumu Ohya, Miki Matsui, Junko Kajikuri, Kyoko Endo and Hiroaki Kito

Journal of Pharmacology and Experimental Therapeutics April 2021, 377 (1) 75-85; DOI: https://doi.org/10.1124/jpet.120.000395
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Enhancement of Opioid Antinociception by Nicotinic Ligands
Fernando B. de Moura and Jack Bergman

Journal of Pharmacology and Experimental Therapeutics April 2021, 377 (1) 100-107; DOI: https://doi.org/10.1124/jpet.120.000423
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Glutathione S-Transferase P Influences Redox Homeostasis and Response to Drugs that Induce the Unfolded Protein Response in Zebrafish
Leilei Zhang, Seok-Hyung Kim, Ki-Hoon Park, Zhi-wei Ye, Jie Zhang, Danyelle M. Townsend and Kenneth D. Tew

Journal of Pharmacology and Experimental Therapeutics April 2021, 377 (1) 121-132; DOI: https://doi.org/10.1124/jpet.120.000417
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A Novel Mitochondrial Complex of Aldosterone Synthase, Steroidogenic Acute Regulatory Protein, and Tom22 Synthesizes Aldosterone in the Rat Heart
Himangshu S. Bose, Randy M. Whittal, Brendan Marshall, Maheshinie Rajapaksha, Ning Ping Wang, Madhuchanda Bose, Elizabeth W. Perry, Zhi-Qing Zhao and Walter L. Miller

Journal of Pharmacology and Experimental Therapeutics April 2021, 377 (1) 108-120; DOI: https://doi.org/10.1124/jpet.120.000365

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