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Characterization of Stressed Transgenic Mice Overexpressing H₂-Histamine Receptors in the Heart
Ulrich Gergs, Uwe Kirchhefer, Fabian Bergmann, Bernhard Künstler, Natascha Mißlinger, Bastian Au, Mareen Mahnkopf, Hartmut Wache and Joachim Neumann

Journal of Pharmacology and Experimental Therapeutics September 2020, 374 (3) 479-488; DOI: https://doi.org/10.1124/jpet.120.000063
Open Access
Beneficial Effects of Soluble Guanylyl Cyclase Stimulation and Activation in Sickle Cell Disease Are Amplified by Hydroxyurea: In Vitro and In Vivo Studies
W.A. Ferreira, H. Chweih, C. Lanaro, C.B. Almeida, P.L. Brito, E.M.F. Gotardo, L. Torres, L.I. Miguel, C.F. Franco-Penteado, F.C. Leonardo, F. Garcia, S.T.O. Saad, P.S. Frenette, D. Brockschnieder, F.F. Costa, J.P. Stasch, P. Sandner and N. Conran

Journal of Pharmacology and Experimental Therapeutics September 2020, 374 (3) 469-478; DOI: https://doi.org/10.1124/jpet.119.264606
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Antiemetic Effects of Cannabinoid Agonists in Nonhuman Primates
Lisa M. Wooldridge, Lipin Ji, Yingpeng Liu, Spyros P. Nikas, Alexandros Makriyannis, Jack Bergman and Brian D. Kangas

Journal of Pharmacology and Experimental Therapeutics September 2020, 374 (3) 462-468; DOI: https://doi.org/10.1124/jpet.120.265710
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Therapeutic Effects of Anti-Inflammatory N-Acylhydrazones in the Resolution of Experimental Colitis
Natália Cordeiro, Rosana Helena Coimbra Nogueira Freitas, Carlos Alberto Manssour Fraga and Patricia Dias Fernandes

Journal of Pharmacology and Experimental Therapeutics September 2020, 374 (3) 420-427; DOI: https://doi.org/10.1124/jpet.120.000074
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Renoprotective Effects of a Novel Receptor-Interacting Protein Kinase 2 Inhibitor, AS3334034, in Uninephrectomized Adriamycin-Induced Chronic Kidney Disease Rats
Yusuke Wada, Mitsuhiro Kondo, Kumi Sakairi, Akira Nagashima, Kenichi Tokita, Hiroaki Tominaga, Hiroshi Tomiyama and Tomohisa Ishikawa

Journal of Pharmacology and Experimental Therapeutics September 2020, 374 (3) 428-437; DOI: https://doi.org/10.1124/jpet.120.265678
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Slow-, Tight-Binding Inhibition of CYP17A1 by Abiraterone Redefines Its Kinetic Selectivity and Dosing Regimen
Eleanor Jing Yi Cheong, Pramod C. Nair, Rebecca Wan Yi Neo, Ho Thanh Tu, Fu Lin, Edmund Chiong, Kesavan Esuvaranathan, Hao Fan, Russell Z. Szmulewitz, Cody J. Peer, William D. Figg, Christina Li Lin Chai, John O. Miners and Eric Chun Yong Chan

Journal of Pharmacology and Experimental Therapeutics September 2020, 374 (3) 438-451; DOI: https://doi.org/10.1124/jpet.120.265868
Open Access
Aripiprazole Cytotoxicity Coincides with Activation of the Unfolded Protein Response in Human Hepatic Cells
Francesca Forno, Yossi Maatuf, Shatha Boukeileh, Priya Dipta, Mohamed Mahameed, Odai Darawshi, Vitor Ferreira, Patricia Rada, Irma García-Martinez, Einav Gross, Avi Priel, Ángela M. Valverde and Boaz Tirosh

Journal of Pharmacology and Experimental Therapeutics September 2020, 374 (3) 452-461; DOI: https://doi.org/10.1124/jpet.119.264481
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Fentanyl but not Morphine Interacts with Nonopioid Recombinant Human Neurotransmitter Receptors and Transporters
Randy Torralva, Amy J. Eshleman, Tracy L. Swanson, Jennifer L. Schmachtenberg, William E. Schutzer, Shelley H. Bloom, Katherine M. Wolfrum, John F. Reed and Aaron Janowsky

Journal of Pharmacology and Experimental Therapeutics September 2020, 374 (3) 376-391; DOI: https://doi.org/10.1124/jpet.120.265561
Open Access
(3S)‐3‐(2,3‐difluorophenyl)‐3‐methoxypyrrolidine (IRL752) —a Novel Cortical-Preferring Catecholamine Transmission- and Cognition-Promoting Agent
S. Hjorth, S. Waters, N. Waters, J. Tedroff, P. Svensson, A. Fagerberg, M. Edling, B. Svanberg, E. Ljung, J. Gunnergren, S.L. McLean, B. Grayson, N.F. Idris, J.C. Neill and C. Sonesson

Journal of Pharmacology and Experimental Therapeutics September 2020, 374 (3) 404-419; DOI: https://doi.org/10.1124/jpet.120.000037
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The Rewarding and Anxiolytic Properties of Ethanol within the Central Nucleus of the Amygdala: Mediated by Genetic Background and Nociceptin
Christopher P. Knight, Sheketha R. Hauser, R. Aaron Waeiss, Andrei I. Molosh, Philip L. Johnson, William A. Truitt, William J. McBride, Richard L. Bell, Anantha Shekhar and Zachary A. Rodd

Journal of Pharmacology and Experimental Therapeutics September 2020, 374 (3) 366-375; DOI: https://doi.org/10.1124/jpet.119.262097

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