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Journal of Pharmacology and Experimental Therapeutics

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Latest Articles

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    Novel Tocolytic Strategy: Modulating Cx43 Activity by S-Nitrosation
    Scott D. Barnett, Hazik Asif, Mitchell T. Anderson and Iain L.O. Buxton
    Journal of Pharmacology and Experimental Therapeutics December 31, 2020, JPET-AR-2020-000427; DOI: https://doi.org/10.1124/jpet.120.000427
  • You have access
    Opening of intermediate conductance Ca2+-activated K+ channels in C2C12 skeletal muscle cells increases the myotube diameter via the Akt/mTOR pathway
    Yuzo Iseki, Yuko Ono, Chihiro Hibi, Shoko Tanaka, Shunya Takeshita, Yuko Maejima, Junko Kurokawa, Masahiro Murakawa, Kenju Shimomura and Kazuho Sakamoto
    Journal of Pharmacology and Experimental Therapeutics December 29, 2020, JPET-AR-2020-000290; DOI: https://doi.org/10.1124/jpet.120.000290
  • You have access
    Identification of a Human Whole Blood-Based Endothelial Cell Impedance Assay for Assessing Clinical TRPV4 Target Engagement Ex Vivo
    Xiaoping Xu, Navin Goyal, Melissa H Costell, Theresa Roethke, Christian H James, Kevin S Thorneloe, Jaclyn R Patterson, Patrick Stoy, Krista Goodman, Dennis L Sprecher and David J Behm
    Journal of Pharmacology and Experimental Therapeutics December 29, 2020, JPET-AR-2020-000307; DOI: https://doi.org/10.1124/jpet.120.000307
  • Open Access
    Amphetamine-like Neurochemical and Cardiovascular Effects of α-Ethylphenethylamine Analogs Found in Dietary Supplements
    Charles W. Schindler, Eric B. Thorndike, John S. Partilla, Kenner C. Rice and Michael H. Baumann
    Journal of Pharmacology and Experimental Therapeutics January 2021, 376 (1) 118-126; DOI: https://doi.org/10.1124/jpet.120.000129
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    Metoprolol Impairs β1-Adrenergic Receptor-Mediated Vasodilation in Rat Cerebral Arteries: Implications for β-Blocker Therapy
    Christopher L. Moore, David S. Henry, Samantha J. McClenahan, Kelly K. Ball, Nancy J. Rusch and Sung W. Rhee
    Journal of Pharmacology and Experimental Therapeutics January 2021, 376 (1) 127-135; DOI: https://doi.org/10.1124/jpet.120.000176
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    Correction to “Characterization of Ubrogepant: A Potent and Selective Antagonist of the Human Calcitonin Gene‒Related Peptide Receptor”
    Journal of Pharmacology and Experimental Therapeutics January 2021, 376 (1) 147; DOI: https://doi.org/10.1124/jpet.119.261065err
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    Therapeutic Effect of Neuraminidase-1–Selective Inhibition in Mouse Models of Bleomycin-Induced Pulmonary Inflammation and Fibrosis
    Irina G. Luzina, Erik P. Lillehoj, Virginia Lockatell, Sang W. Hyun, Katerina N. Lugkey, Akihiro Imamura, Hideharu Ishida, Christopher W. Cairo, Sergei P. Atamas and Simeon E. Goldblum
    Journal of Pharmacology and Experimental Therapeutics January 2021, 376 (1) 136-146; DOI: https://doi.org/10.1124/jpet.120.000223
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    Self-administration of cotinine in Wistar rats: comparisons to nicotine
    Zheng-Ming Ding, Yong Gao, Alena Sentir and Xiaoying Tan
    Journal of Pharmacology and Experimental Therapeutics December 23, 2020, JPET-AR-2020-000367; DOI: https://doi.org/10.1124/jpet.120.000367
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    Manipulating Pharmacodynamic Efficacy with Agonist + Antagonist Mixtures:In Vitro and In Vivo Studies with Opioids and Cannabinoids
    Dana E. Selley, Matthew L. Banks, Clare M Diester, Abdul M Jali, Luke P. Legakis, Edna J Santos and S. Stevens Negus
    Journal of Pharmacology and Experimental Therapeutics December 22, 2020, JPET-AR-2020-000349; DOI: https://doi.org/10.1124/jpet.120.000349
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    RNAi targeting liver Angiopoietin-like protein 3 protects from nephrotic syndrome in a rat model via amelioration of pathologic hypertriglyceridemia
    Yitong Zhao, Masaki Goto, Nosratola D Vaziri, Mahyar Khazaeli, Han Liu, Nazli Farahanchi, Elham Khanifar, Ted Farzaneh, Patrick A Haslett, Hamid Moradi and Mangala M Soundarapandian
    Journal of Pharmacology and Experimental Therapeutics December 18, 2020, JPET-AR-2020-000257; DOI: https://doi.org/10.1124/jpet.120.000257

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ISSN 1521-0103 (Online)

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