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Development of CVN424: A Selective and Novel GPR6 Inverse Agonist Effective in Models of Parkinson Disease
Nicola L. Brice, Hans H. Schiffer, Holger Monenschein, Victoria J. Mulligan, Keith Page, Justin Powell, Xiao Xu, Toni Cheung, J. Russell Burley, Huikai Sun, Louise Dickson, Sean T. Murphy, Nidhi Kaushal, Steve Sheardown, Jason Lawrence, Yun Chen, Darian Bartkowski, Anne Kanta, Joseph Russo, Natalie Hosea, Lee A. Dawson, Stephen H. Hitchcock and Mark B. Carlton

Journal of Pharmacology and Experimental Therapeutics June 2021, 377 (3) 407-416; DOI: https://doi.org/10.1124/jpet.120.000438
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Brain Concentrations of Methylone and Its Metabolites after Systemic Methylone Administration: Relationship to Pharmacodynamic Effects
Nicole Centazzo, Michael R. Chojnacki, Joshua S. Elmore, Raider Rodriguez, Teeshavi Acosta, Masaki Suzuki, Kenner C. Rice, Michael H. Baumann and Marta Concheiro

Journal of Pharmacology and Experimental Therapeutics June 2021, 377 (3) 398-406; DOI: https://doi.org/10.1124/jpet.121.000531
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Liver-specific, non-viral gene delivery of fibroblast growth factor 21 protein expression in mice regulates body mass and white/brown fat respiration
NATHANIEL GIRER, Victoria G Rontoyanni, Aditya Joshi, Igor Patrikeev, Andrew J Murton, Craig Porter, Massoud Motamedi and Cornelis Elferink

Journal of Pharmacology and Experimental Therapeutics June 1, 2021, JPET-AR-2021-000514; DOI: https://doi.org/10.1124/jpet.121.000514
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In Vitro Assessment of the Drug-Drug Interaction Potential of Verinurad and its Metabolites as Substrates and Inhibitors of Metabolizing Enzymes and Drug Transporters
V. Sashi Gopaul, Anna Vildhede, Tommy B Andersson, Fredrik Erlandsson, Caroline A. Lee, Susanne Johansson and Constanze Hilgendorf

Journal of Pharmacology and Experimental Therapeutics June 1, 2021, JPET-AR-2021-000549; DOI: https://doi.org/10.1124/jpet.121.000549
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Evaluation of Ipatasertib Interactions with Itraconazole and Coproporphyrin I and III in a Single Drug Interaction Study in Healthy Subjects
Rucha Sane, Kit Wun Kathy Cheung, Eunpi Cho, Bianca M Liederer, Justin Hanover, Vikram Malhi, Emile Plise, Susan Wong and Luna Musib

Journal of Pharmacology and Experimental Therapeutics May 28, 2021, JPET-AR-2021-000620; DOI: https://doi.org/10.1124/jpet.121.000620
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Comments on “Pharmacological Characterization of Apraglutide a Novel Long-Acting Peptidic Glucagon-Like Peptide-2 Agonist for the Treatment of Short Bowel Syndrome”
Jolanta Skarbaliene, Bjarne Due Larsen, Mark Berner-Hansen and Adam Steensberg

Journal of Pharmacology and Experimental Therapeutics June 2021, 377 (3) 369; DOI: https://doi.org/10.1124/jpet.120.000426
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Synergistic Pharmacodynamic Effects of Gemcitabine and Fibroblast Growth Factor Receptor Inhibitors on Pancreatic Cancer Cell Cycle Kinetics and Proliferation
Qingxiang Lin, Zhicheng Qian, William J. Jusko, Donald E. Mager, Wen Wee Ma and Robert M. Straubinger

Journal of Pharmacology and Experimental Therapeutics June 2021, 377 (3) 370-384; DOI: https://doi.org/10.1124/jpet.120.000412
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Correction to “Pharmacological Characterization of Apraglutide, a Novel Long-Acting Peptidic Glucagon-Like Peptide-2 Agonist, for the Treatment of Short Bowel Syndrome”
Journal of Pharmacology and Experimental Therapeutics June 2021, 377 (3) 368; DOI: https://doi.org/10.1124/jpet.119.262238err
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A comparison of breathing stimulants for reversal of synthetic opioid-induced respiratory depression in conscious rats
Kaye Elizabeth Dandrea and Joseph Frank Cotten

Journal of Pharmacology and Experimental Therapeutics May 21, 2021, JPET-AR-2021-000675; DOI: https://doi.org/10.1124/jpet.121.000675
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Novel Antimuscarinic Antidepressant-like Compounds with Reduced Effects on Cognition
Chad R. Johnson, Brian D. Kangas, Emily M. Jutkiewicz, Gail Winger, Jack Bergman, Andrew Coop and James H. Woods

Journal of Pharmacology and Experimental Therapeutics June 2021, 377 (3) 336-345; DOI: https://doi.org/10.1124/jpet.120.000337

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