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Untargeted Metabolomics Reveals Anaerobic Glycolysis as a Novel Target of the Hepatotoxic Antidepressant Nefazodone
Evelin Krajnc, Michele Visentin, Zhibo Gai, Bruno Stieger, Sophia L. Samodelov, Stephanie Häusler and Gerd A. Kullak-Ublick

Journal of Pharmacology and Experimental Therapeutics November 2020, 375 (2) 239-246; DOI: https://doi.org/10.1124/jpet.120.000120
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Mifepristone Decreases Chronic Voluntary Ethanol Consumption in Rhesus Macaques
Vanessa A. Jimenez, Nicole A.R. Walter, Tatiana A. Shnitko, Natali Newman, Kaya Diem, Lauren Vanderhooft, Hazel Hunt and Kathleen A. Grant

Journal of Pharmacology and Experimental Therapeutics November 2020, 375 (2) 258-267; DOI: https://doi.org/10.1124/jpet.120.000169
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A Novel Potent and Selective Histamine H₃ Receptor Antagonist Enerisant: In Vitro Profiles, In Vivo Receptor Occupancy, and Wake-Promoting and Procognitive Effects in Rodents
Noriko Hino, Toshiyuki Marumo, Makiko Kotani, Toshiharu Shimazaki, Ayaka Kaku-Fukumoto, Hirohiko Hikichi, Jun-ichi Karasawa, Yasumitsu Tomishima, Hiroko Komiyama, Emi Tatsuda, Dai Nozawa, Toshio Nakamura and Shigeyuki Chaki

Journal of Pharmacology and Experimental Therapeutics November 2020, 375 (2) 276-285; DOI: https://doi.org/10.1124/jpet.120.000185
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Angiotensin-(1–7) Rescues Chronic Intermittent Hypoxia-Aggravated Transforming Growth Factor-β–Mediated Airway Remodeling in Murine and Cellular Models of Asthma
Jian Ping Zhou, Ying Ni Lin, Ning Li, Xian Wen Sun, Yong Jie Ding, Ya Ru Yan, Liu Zhang and Qing Yun Li

Journal of Pharmacology and Experimental Therapeutics November 2020, 375 (2) 268-275; DOI: https://doi.org/10.1124/jpet.120.000150
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Protective Mechanism of the Selective Vasopressin V_1A Receptor Agonist Selepressin against Endothelial Barrier Dysfunction
Nektarios Barabutis, Margarita Marinova, Pavel Solopov, Mohammad A. Uddin, Glenn E. Croston, Torsten M. Reinheimer and John D. Catravas

Journal of Pharmacology and Experimental Therapeutics November 2020, 375 (2) 286-295; DOI: https://doi.org/10.1124/jpet.120.000146
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Celastrol Dilates and Counteracts Ethanol-Induced Constriction of Cerebral Arteries
Kelsey North, Alexandria Slayden, Steven Mysiewicz, Anna Bukiya and Alex Dopico

Journal of Pharmacology and Experimental Therapeutics November 2020, 375 (2) 247-257; DOI: https://doi.org/10.1124/jpet.120.000152
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Targeted Injection of a Truncated Form of Tissue Inhibitor of Metalloproteinase 3 Alters Post–Myocardial Infarction Remodeling
David C. Lobb, Heather Doviak, Gregory L. Brower, Eva Romito, Jason W. O’Neill, Stephen Smith, James A. Shuman, Parker D. Freels, Kia N. Zellars, Lisa A. Freeburg, Aarif Y. Khakoo, TaeWeon Lee and Francis G. Spinale

Journal of Pharmacology and Experimental Therapeutics November 2020, 375 (2) 296-307; DOI: https://doi.org/10.1124/jpet.120.000047
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An evaluation of the activity of histidine-rich glycoprotein on differentiated neutrophil-like cells from human cell lines
Yukinori Yoshii, Hidenori Wake, Yoshito Nishimura, Kiyoshi Teshigawara, Dengli Wang and Masahiro Nishibori

Journal of Pharmacology and Experimental Therapeutics October 19, 2020, JPET-AR-2020-000182; DOI: https://doi.org/10.1124/jpet.120.000182
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Mechanism of Action of Veverimer: A Novel, Orally Administered, Non-absorbed, Counterion-Free, Hydrochloric Acid Binder under Development for the Treatment of Metabolic Acidosis in Chronic Kidney Disease
Gerrit Klaerner, Jun Shao, Kalpesh Biyani, Matthew Kade, Paul Kierstead, Randi Gbur, Scott Tabakman, Son Nguyen and Jerry Buysse

Journal of Pharmacology and Experimental Therapeutics October 8, 2020, JPET-AR-2020-000190; DOI: https://doi.org/10.1124/jpet.120.000190
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The Role of Smoking and Nicotine in the Transmission and Pathogenesis of COVID-19
Ali Ehsan Sifat, Saeideh Nozohouri, Heidi Villalba, Bhuvaneshwar Vaidya and Thomas J. Abbruscato

Journal of Pharmacology and Experimental Therapeutics October 8, 2020, JPET-MR-2020-000170; DOI: https://doi.org/10.1124/jpet.120.000170

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