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Rosuvastatin inhibits the apoptosis of platelet-derived growth factor-stimulated vascular smooth muscle cells by inhibiting p38 via autophagy
Jun-Hwan Jo, Hyun-Soo Park, Do-Hyung Lee, Joo-Hui Han, Kyung-Sun Heo and Chang-Seon Myung

Journal of Pharmacology and Experimental Therapeutics April 12, 2021, JPET-AR-2021-000539; DOI: https://doi.org/10.1124/jpet.121.000539
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Increasing effects of selective 5-HT_2C receptor stimulation on evoked momentary urethral closure in female rats and humans
Izumi Kamo, Hiroshi Nagata, Gale O'Connell, Takuya Kato, Akio Imanishi, Masako Kuno, Satoshi Okanishi, Kyoko Yoshikawa and Yuya Nishiyama

Journal of Pharmacology and Experimental Therapeutics April 9, 2021, JPET-AR-2021-000573; DOI: https://doi.org/10.1124/jpet.121.000573
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Possible Involvement of Muscarinic Receptor Blockade in Mirabegron Therapy for Patients with Overactive Bladder
Shizuo Yamada, Junko Chimoto, Mizuki Shiho, Takashi Okura, Kana Morikawa, Hirokazu Wakuda and Kazumasa Shinozuka

Journal of Pharmacology and Experimental Therapeutics May 2021, 377 (2) 201-206; DOI: https://doi.org/10.1124/jpet.120.000301
Open Access
An Integrative Approach for Improved Assessment of Cardiovascular Safety Data
Mikael Wallman, Stefan Scheuerer, Eric Martel, Nicolas Pairet, Mats Jirstrand and Johan Gabrielsson

Journal of Pharmacology and Experimental Therapeutics May 2021, 377 (2) 218-231; DOI: https://doi.org/10.1124/jpet.120.000348
Open Access
Stem Cell Therapies in Alzheimer’s Disease: Applications for Disease Modeling
Zizhen Si and Xidi Wang

Journal of Pharmacology and Experimental Therapeutics May 2021, 377 (2) 207-217; DOI: https://doi.org/10.1124/jpet.120.000324
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Poly (ADP-ribose) polymerase inhibitors for arsenic trioxide-resistant acute promyelocytic leukemia: synergistic in vitro antitumor effects with hypomethylating agents or high-dose vitamin C
Manuela Giansanti, Antonio De Gabrieli, Salvatore Pasquale Prete, Tiziana Ottone, Maria Domenica Divona, Terry Karimi, Fabio Ciccarone, Maria Teresa Voso, Grazia Graziani and Isabella Faraoni

Journal of Pharmacology and Experimental Therapeutics April 5, 2021, JPET-AR-2021-000537; DOI: https://doi.org/10.1124/jpet.121.000537
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Ginsenoside Ro ameliorates high fat diet-induced obesity and insulin resistance in mice via activation of the TGR5 pathway
Lin-shan Jiang, Wei Li, Tong-xi Zhuang, Jie-jing Yu, Shuai Sun, Zheng-cai Ju, Zheng-tao Wang, Li-li Ding and Li Yang

Journal of Pharmacology and Experimental Therapeutics April 5, 2021, JPET-AR-2020-000435; DOI: https://doi.org/10.1124/jpet.120.000435
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Development of CVN424: a selective and novel GPR6 inverse agonist effective in models of Parkinson's Disease
Nicola L Brice, Hans H Schiffer, Holger Monenschein, Victoria J Mulligan, Keith Page, Justin Powell, Xiao Xu, Toni Cheung, J Russell Burley, Huikai Sun, Louise Dickson, Sean T Murphy, Nidhi Kaushal, Steven Sheardown, Jason Lawrence, Yun Chen, Darian Bartkowski, Anne Kanta, Joseph Russo, Natalie Hosea, Lee A Dawson, Stephen H Hitchcock and Mark B Carlton

Journal of Pharmacology and Experimental Therapeutics April 1, 2021, JPET-AR-2020-000438; DOI: https://doi.org/10.1124/jpet.120.000438
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Brain Concentrations of Methylone and its Metabolites After Systemic Methylone Administration: Relationship to Pharmacodynamic Effects
Nicole Centazzo, Michel R Chojnacki, Joshua S Elmore, Raider Rodriguez, Teeshavi Acosta, Masaki Suzuki, Kenner C Rice, Michael H Baumann and Marta Concheiro

Journal of Pharmacology and Experimental Therapeutics March 30, 2021, JPET-AR-2021-000531; DOI: https://doi.org/10.1124/jpet.121.000531
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Characterization of Novel Fluorescent Bile Salt Derivatives for Studying Human Bile Salt and Organic Anion Transporters
Michele Leuenberger, Stephanie Häusler, Vera Höhn, Adriana Euler, Bruno Stieger and Martin Lochner

Journal of Pharmacology and Experimental Therapeutics March 29, 2021, JPET-AR-2020-000449; DOI: https://doi.org/10.1124/jpet.120.000449

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