Abstract
1. It is shown that the toxicity of 2,4-dinitrophenol in the adult albino mouse is lowered by decrease and raised by increase of environmental temperature between 6° and 40°C.
2. Calculated values of the LD50, for DNP in mgm. per kgm. were 35.7 and 30.9 at 6° and 25° respectively. The difference between these values is significant
3. The LD50 at 40°C. was not determined. However, it is shown that it lies below 8.22 mgm. DNP per kgm. and is significantly lower than the 25°C. value.
Footnotes
- Received July 15, 1943.