Abstract
1. Experiments designed to show a specific antagonism between sodium thiocyanate and several narcotic agents have failed entirely to support the claims made by Bancroft and Reitzler that a marked decrease in anaesthesia and a marked increase in respiration is produced by the administration of sodium thiocyanate.
2. A discussion of Bancroft's statement of the Claude Bernard theory of narcosis shows that Bancroft has not been able to demonstrate that coagulation (as the term is usually understood) always accompanies narcosis. This and other evidence which is so ably presented by Winterstein (22) (p. 357-60), and discussed more briefly by Henderson (15), leads us to reject a coagulation theory of narcosis. And this is true, even if we use the word "coagulation" with the Bancroft connotation.
JPET articles become freely available 12 months after publication, and remain freely available for 5 years.Non-open access articles that fall outside this five year window are available only to institutional subscribers and current ASPET members, or through the article purchase feature at the bottom of the page.
|