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Journal of Pharmacology and Experimental Therapeutics

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Fast Forward

JPET Fast Forward contains papers in manuscript form that have been accepted and published in JPET but have not been copyedited and have not been assigned to an issue of the journal. Copyediting may lead to some differences between the Fast Forward version and the final version. There may also be differences in the quality of the graphics. The publication date appears below each title followed by the article's unique Digital Object Identifier (DOI).

May 24, 2022

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    The functions and mechanisms of translatable circRNAs
    Chang Liu, Xinying Wu, Priyanka Gokulnath, Guoping Li and Junjie Xiao
    Journal of Pharmacology and Experimental Therapeutics May 24, 2022, JPET-MR-2022-001085; DOI: https://doi.org/10.1124/jpet.122.001085
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    8-Aminoinosine and 8-Aminohypoxanthine Inhibit Purine Nucleoside Phosphorylase and Exert Diuretic and Natriuretic Activity
    Edwin K. Jackson, Elizabeth V. Menshikova, Vladimir B. Ritov, Zaichuan Mi and Lori A. Birder
    Journal of Pharmacology and Experimental Therapeutics May 24, 2022, JPET-AR-2022-001221; DOI: https://doi.org/10.1124/jpet.122.001221

May 05, 2022

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    Sodium pentobarbital suppresses breast cancer cells growth partly via normalizing microcirculatory hemodynamics and oxygenation in tumors
    Qin Wang, Xueting Liu, Bingwei Li, Xiaojie Yang, Wenbao Lu, Ailing Li, Hongwei Li, Xiaoyan Zhang and Jianqun Han
    Journal of Pharmacology and Experimental Therapeutics May 5, 2022, JPET-AR-2021-001058; DOI: https://doi.org/10.1124/jpet.121.001058
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    Optimized S-nitrosohemoglobin synthesis in red blood cells to preserve hypoxic vasodilation via βCys93
    Alfred Hausladen, Zhaoxia Qian, Rongli Zhang, Richard T. Premont and Jonathan S. Stamler
    Journal of Pharmacology and Experimental Therapeutics May 5, 2022, JPET-AR-2022-001194; DOI: https://doi.org/10.1124/jpet.122.001194

May 03, 2022

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    Treatment of γ-Hydroxybutyrate (GHB) Overdose with the GABAB Antagonist SGS742
    Kristin E Follman and Marilyn E. Morris
    Journal of Pharmacology and Experimental Therapeutics May 3, 2022, JPET-AR-2022-001108; DOI: https://doi.org/10.1124/jpet.122.001108

April 30, 2022

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    Fate determination role of erythropoietin and romiplostim in the lineage commitment of hematopoietic progenitors
    Xiaoqing Fan, Wojciech Krzyzanski, Raymond S. M. Wong and Xiaoyu Yan
    Journal of Pharmacology and Experimental Therapeutics April 30, 2022, JPET-AR-2022-001130; DOI: https://doi.org/10.1124/jpet.122.001130
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    Preclinical assessment of the abuse potential of purified botanical cannabidiol: self-administration, drug discrimination, and physical dependence
    Royston A Gray, David J Heal, David R. Maguire, Lisa R. Gerak, Martin A. Javors, Sharon Smith and Charles P. France
    Journal of Pharmacology and Experimental Therapeutics April 30, 2022, JPET-AR-2021-000988; DOI: https://doi.org/10.1124/jpet.121.000988
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    Role of Efficacy as a Determinant of Locomotor Activation by Mu Opioid Receptor Ligands in Female and Male Mice
    Edna J. Santos, Matthew L. Banks and S Stevens Negus
    Journal of Pharmacology and Experimental Therapeutics April 30, 2022, JPET-AR-2021-001045; DOI: https://doi.org/10.1124/jpet.121.001045

April 09, 2022

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    Ligustrazine attenuates liver fibrosis by targeting miR-145 mediated TGF-β/Smad signaling in an animal model of biliary atresia
    Jian-Li Qiu, Guo-Feng Zhang, Yu-Na Chai, Xiao-Yan Han, Hai-Tao Zheng, Xiang-Feng Li, Fei Duan and Ling-Yan Chen
    Journal of Pharmacology and Experimental Therapeutics April 9, 2022, JPET-AR-2021-001020; DOI: https://doi.org/10.1124/jpet.121.001020

April 05, 2022

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    Anisodamine enhances macrophage M2 polarization through suppressing G9a-mediated IRF4 silencing to alleviate LPS-induced acute lung injury
    Yunfeng Zhang, Dingli Song, Ziyang Peng, Rui Wang, Kai Li, Hong Ren, Xin Sun, Ning Du and Shou-Ching Tang
    Journal of Pharmacology and Experimental Therapeutics April 5, 2022, JPET-AR-2021-001019; DOI: https://doi.org/10.1124/jpet.121.001019

April 03, 2022

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    CNS delivery of the DNA-PKcs inhibitor peposertib as radiosensitizer for brain metastases
    Surabhi Talele, Wenjuan Zhang, Ju-Hee Oh, Danielle M. Burgenske, Ann C Mladek, Sonja Dragojevic, Jann N. Sarkaria and William F. Elmquist
    Journal of Pharmacology and Experimental Therapeutics April 3, 2022, JPET-AR-2021-001069; DOI: https://doi.org/10.1124/jpet.121.001069

March 28, 2022

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    Anesthetic preconditioning of traumatic brain injury is ineffective in a Drosophila model of obesity
    Dena Johnson-Schlitz, Julie A Fischer, Hannah J Schiffman, Amanda R Scharenbrock, Zachariah PG Olufs, David A Wassarman and Misha Perouansky
    Journal of Pharmacology and Experimental Therapeutics March 28, 2022, JPET-AR-2021-000997; DOI: https://doi.org/10.1124/jpet.121.000997
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    ACE2 inhibits lipopolysaccharide-caused lung fibrosis via downregulating the TGF-β1/Smad2/Smad3 pathway
    Xingsheng Lin, Wenhao Lin, Yingfeng Zhuang and Fengying Gao
    Journal of Pharmacology and Experimental Therapeutics March 28, 2022, JPET-AR-2021-000907; DOI: https://doi.org/10.1124/jpet.121.000907

March 26, 2022

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    L-Arginine Enhances the Effects of Cardiac Rehabilitation on Physical Performance: New Insights for Managing Cardiovascular Patients During the COVID-19 Pandemic
    Pasquale Mone, Raffaele Izzo, Giuseppe Marazzi, Maria Virginia Manzi, Paola Gallo, Giuseppe Campolongo, Luca Cacciotti, Domenico Tartaglia, Giuseppe Caminiti, Fahimeh Varzideh, Gaetano Santulli and Valentina Trimarco
    Journal of Pharmacology and Experimental Therapeutics March 26, 2022, JPET-AR-2022-001149; DOI: https://doi.org/10.1124/jpet.122.001149

March 24, 2022

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    CARDIAC ANTHRACYCLINE ACCUMULATION AND B-TYPE NATRIURETIC PEPTIDE TO DEFINE RISK AND PREDICTORS OF CANCER TREATMENT RELATED EARLY DIASTOLIC DYSFUNCTION
    Giorgio Minotti, Emanuela Salvatorelli, Giorgio Reggiardo, Fabio Mangiacapra, Massimiliano Camilli and Pierantonio Menna
    Journal of Pharmacology and Experimental Therapeutics March 24, 2022, JPET-AR-2022-001101; DOI: https://doi.org/10.1124/jpet.122.001101

March 19, 2022

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    Neutrophil-derived Myeloperoxidase and Hypochlorous Acid Critically Contribute to 20-HETE Increases that Drive Post-Ischemic Angiogenesis
    Juan A Azcona, Samantha Tang, Elizabeth Berry, Frank F Zhang, Radha Garvey, John R Falck, Michal Laniado Schwartzman, Tao Yi, Thomas M Jeitner and Austin M Guo
    Journal of Pharmacology and Experimental Therapeutics March 19, 2022, JPET-AR-2021-001036; DOI: https://doi.org/10.1124/jpet.121.001036

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