Article Figures & Data
Additional Files
Data Supplement
- Supplemental Data -
Supplementary figure 1. Weight of control and G1D mice.
Supplementary figure 2. Sex differences in weight, blood glucose concentration and behavior for control and G1D mice.
Supplementary table 1. Salient publications on top Prestwick-NIH glucose transport activators relevant to Glut1-related aspects.
Supplementary table 2. 91 NIH-Prestwick activators from the initial screening (77 Prestwick; 14 NIH Clinical).
Supplementary table 3. 6 NIH and Prestwick inhibitors identified in the initial screening
Supplementary table 4. 30 NIH and Prestwick activators and inhibitors that proceeded to dose response (0.86, 2.5 and 7.5 uM) and autofluorescence (>1.0 Robust Z score at 2.5μM) confirmation.
Supplementary table 5. 6 NIH and Prestwick activators without autofluorescence and confirmation at all 3 doses.
Supplementary table 6. 4 NIH-Prestwick activators without autofluorescence and confirmation at 2 doses.
Supplementary table 7. 8K Diversity Screen activators and inhibitors.
Supplementary table 8. 7 Inhibitors confirmed from the 8K Diversity library.
- Supplementary Material 1 -
Supplementary material 1. Primary screening activator results for Prestwick and NIH libraries.
- Supplementary Material 2 -
Supplementary material 2. Primary screening inhibitor results for Prestwick and NIH libraries.
- Supplementary Material 3 -
Supplementary material 3. Confirmatory screening activator and inhibitor results for Prestwick and NIH libraries.
- Supplementary Material 4 -
Supplementary material 4. Primary screening activator results for 8K diversity library.
- Supplementary Material 5 -
Supplementary material 5. Primary screening inhibitor results for 8K diversity library.
- Supplementary Material 6 -
Supplementary material 6. Confirmatory screening activator results for 8K diversity library.
- Supplementary Material 7 -
Supplementary material 7. Confirmatory screening inhibitor results for 8K diversity library.
- Supplemental Data -
