Specific Lowering of ADMA by Pharmacological DDAH Improves Endothelial Function, Reduces Blood Pressure and Ischemia-Reperfusion Injury

Young Lee; Purvi Mehrotra; David Basile; MD Mahbub Ullah; Arshnoor Singh; Nicholas Skill; Subhi Talal Younes; Jennifer Sasser; Anantha Shekhar; Jaipal Singh

doi:10.1124/jpet.120.000212

OtherCardiovascular

Specific Lowering of ADMA by Pharmacological DDAH Improves Endothelial Function, Reduces Blood Pressure and Ischemia-Reperfusion Injury

Young Lee, Purvi Mehrotra, David Basile, MD Mahbub Ullah, Arshnoor Singh, Nicholas Skill, Subhi Talal Younes, Jennifer Sasser, Anantha Shekhar and Jaipal Singh

Journal of Pharmacology and Experimental Therapeutics November 19, 2020, JPET-AR-2020-000212; DOI: https://doi.org/10.1124/jpet.120.000212

Young Lee

1Indiana Center for Biomedical Innovation, United States of America

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Purvi Mehrotra

2Indiana University School of Medicine, United States of America

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David Basile

2Indiana University School of Medicine, United States of America

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MD Mahbub Ullah

2Indiana University School of Medicine, United States of America

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Arshnoor Singh

1Indiana Center for Biomedical Innovation, United States of America

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Nicholas Skill

2Indiana University School of Medicine, United States of America

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Subhi Talal Younes

3University of Mississippi Medical Center, United States of America

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Jennifer Sasser

3University of Mississippi Medical Center, United States of America

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Anantha Shekhar

2Indiana University School of Medicine, United States of America

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Jaipal Singh

4ICBI, Indiana University, United States of America

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For correspondence: singh52@iupui.edu

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Article Information

JPET-AR-2020-000212

DOI

https://doi.org/10.1124/jpet.120.000212

PubMed

33214214

Published By

American Society for Pharmacology and Experimental Therapeutics

Print ISSN

0022-3565

Online ISSN

1521-0103

History

Published online November 19, 2020.

Author Information

Young Lee1,
Purvi Mehrotra2,
David Basile2,
MD Mahbub Ullah2,
Arshnoor Singh1,
Nicholas Skill2,
Subhi Talal Younes3,
Jennifer Sasser3,
Anantha Shekhar2, and
Jaipal Singh4,*

¹Indiana Center for Biomedical Innovation, United States of America
²Indiana University School of Medicine, United States of America
³University of Mississippi Medical Center, United States of America
⁴ICBI, Indiana University, United States of America

↵* Corresponding Author:
Jaipal Singh, ICBI, Indiana University, 13662 Frenchamns Ck, 13662 Frenchamns Ck, 13662 Frenchamns Ck, Carmel, 46932, United States of America. E-mail: singh52{at}iupui.edu

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Article usage: November 2020 to January 2021

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Dec 2020	114	52
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OtherCardiovascular

Therapeutic Potential of Pharmacological DDAH

Young Lee, Purvi Mehrotra, David Basile, MD Mahbub Ullah, Arshnoor Singh, Nicholas Skill, Subhi Talal Younes, Jennifer Sasser, Anantha Shekhar and Jaipal Singh

Journal of Pharmacology and Experimental Therapeutics November 19, 2020, JPET-AR-2020-000212; DOI: https://doi.org/10.1124/jpet.120.000212

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OtherCardiovascular

Therapeutic Potential of Pharmacological DDAH

Young Lee, Purvi Mehrotra, David Basile, MD Mahbub Ullah, Arshnoor Singh, Nicholas Skill, Subhi Talal Younes, Jennifer Sasser, Anantha Shekhar and Jaipal Singh

Journal of Pharmacology and Experimental Therapeutics November 19, 2020, JPET-AR-2020-000212; DOI: https://doi.org/10.1124/jpet.120.000212

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