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Research ArticleInflammation, Immunopharmacology, and Asthma

Topical Application of ASN008, a Permanently-charged Sodium Channel Blocker, Shows Robust Efficacy, a Rapid Onset and Long Duration of Action in a Mouse Model of Pruritus

Roshni Ramachandran, Scott K. Thompson, Shelle Malkmus, Sandeep Gupta, Tsutomu Mieda, Jun-Hsiang Lin and Tony L Yaksh
Journal of Pharmacology and Experimental Therapeutics July 2, 2020, jpet.120.265074; DOI: https://doi.org/10.1124/jpet.120.265074

Article Information

jpet.120.265074
DOI 
https://doi.org/10.1124/jpet.120.265074
PubMed 
32616515
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Published online July 2, 2020.

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Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Roshni Ramachandran1,
  2. Scott K. Thompson2,
  3. Shelle Malkmus1,
  4. Sandeep Gupta2,
  5. Tsutomu Mieda3,
  6. Jun-Hsiang Lin2, and
  7. Tony L Yaksh3,*
  1. 1 Department of Anesthesiology, UCSD, 214 Dickenson Street, San Diego, CA 92103, USA;
  2. 2 Asana BioSciences, 1997 Lenox Drive, Suite 220, Princeton Pike Corporate Center, Lawrenceville, NJ 0;
  3. 3 UC San Diego
  1. ↵*Address correspondence to: tyaksh{at}ucsd.edu

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Research ArticleInflammation, Immunopharmacology, and Asthma

Topical Application of ASN008, a Permanently-charged Sodium Channel Blocker, Shows Robust Efficacy, a Rapid Onset and Long Duration of Action in a Mouse Model of Pruritus

Roshni Ramachandran, Scott K. Thompson, Shelle Malkmus, Sandeep Gupta, Tsutomu Mieda, Jun-Hsiang Lin and Tony L Yaksh
Journal of Pharmacology and Experimental Therapeutics July 2, 2020, jpet.120.265074; DOI: https://doi.org/10.1124/jpet.120.265074
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