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Research ArticleMetabolism, Transport, and Pharmacogenomics

Delineating the role of various factors in renal disposition of digoxin through application of physiologically-based kidney model to renal impairment populations

Daniel Scotcher, Christopher R. Jones, Aleksandra Galetin and Amin Rostami-Hodjegan
Journal of Pharmacology and Experimental Therapeutics January 5, 2017, jpet.116.237438; DOI: https://doi.org/10.1124/jpet.116.237438

Article Information

jpet.116.237438
DOI 
https://doi.org/10.1124/jpet.116.237438
PubMed 
28057840
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Published online January 5, 2017.

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Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Daniel Scotcher1,
  2. Christopher R. Jones2,
  3. Aleksandra Galetin1, and
  4. Amin Rostami-Hodjegan1,*
  1. 1 University of Manchester;
  2. 2 AstraZeneca
  1. ↵*Address correspondence to: amin.rostami{at}manchester.ac.uk

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Research ArticleMetabolism, Transport, and Pharmacogenomics

Delineating the role of various factors in renal disposition of digoxin through application of physiologically-based kidney model to renal impairment populations

Daniel Scotcher, Christopher R. Jones, Aleksandra Galetin and Amin Rostami-Hodjegan
Journal of Pharmacology and Experimental Therapeutics January 5, 2017, jpet.116.237438; DOI: https://doi.org/10.1124/jpet.116.237438
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