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Research ArticleMetabolism, Transport, and Pharmacogenomics

Quantitative prediction of transporter- and enzyme-mediated clinical drug-drug interactions of OATP1B1 substrates using a mechanistic net-effect model

Manthena Varma, Yi-an Bi, Emi Kimoto and Jian Lin
Journal of Pharmacology and Experimental Therapeutics August 8, 2014, jpet.114.215970; DOI: https://doi.org/10.1124/jpet.114.215970

Article Information

jpet.114.215970
DOI 
https://doi.org/10.1124/jpet.114.215970
PubMed 
25107633
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Published online August 8, 2014.

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Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Manthena Varma*,
  2. Yi-an Bi,
  3. Emi Kimoto, and
  4. Jian Lin
  1. Pfizer
  1. ↵* Corresponding author; email: manthena.v.varma{at}pfizer.com

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Research ArticleMetabolism, Transport, and Pharmacogenomics

Quantitative prediction of transporter- and enzyme-mediated clinical drug-drug interactions of OATP1B1 substrates using a mechanistic net-effect model

Manthena Varma, Yi-an Bi, Emi Kimoto and Jian Lin
Journal of Pharmacology and Experimental Therapeutics August 8, 2014, jpet.114.215970; DOI: https://doi.org/10.1124/jpet.114.215970
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