Potent and specific inhibition of mMate1-mediated efflux of type I organic cations in the liver and kidney by pyrimethamine

Sumito Ito; Hiroyuki Kusuhara; Yushun Kuroiwa; Chunyong Wu; Yoshinori Moriyama; Katsuhisa Inoue; Tsunenori Kondo; Hiroaki Yuasa; Hideki Nakayama; Shigeru Horita; Yuichi Sugiyama

doi:10.1124/jpet.109.163642

Research ArticleGastrointestinal, Hepatic, Pulmonary, and Renal

Potent and specific inhibition of mMate1-mediated efflux of type I organic cations in the liver and kidney by pyrimethamine

Sumito Ito, Hiroyuki Kusuhara, Yushun Kuroiwa, Chunyong Wu, Yoshinori Moriyama, Katsuhisa Inoue, Tsunenori Kondo, Hiroaki Yuasa, Hideki Nakayama, Shigeru Horita and Yuichi Sugiyama

Journal of Pharmacology and Experimental Therapeutics January 11, 2010, jpet.109.163642; DOI: https://doi.org/10.1124/jpet.109.163642

Sumito Ito

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Hiroyuki Kusuhara

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Yushun Kuroiwa

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Chunyong Wu

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Yoshinori Moriyama

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Katsuhisa Inoue

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Tsunenori Kondo

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Hiroaki Yuasa

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Hideki Nakayama

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Shigeru Horita

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Yuichi Sugiyama

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Research ArticleGastrointestinal, Hepatic, Pulmonary, and Renal

Potent and specific inhibition of mMate1-mediated efflux of type I organic cations in the liver and kidney by pyrimethamine

Sumito Ito, Hiroyuki Kusuhara, Yushun Kuroiwa, Chunyong Wu, Yoshinori Moriyama, Katsuhisa Inoue, Tsunenori Kondo, Hiroaki Yuasa, Hideki Nakayama, Shigeru Horita and Yuichi Sugiyama

Journal of Pharmacology and Experimental Therapeutics January 11, 2010, jpet.109.163642; DOI: https://doi.org/10.1124/jpet.109.163642

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Research ArticleGastrointestinal, Hepatic, Pulmonary, and Renal

Potent and specific inhibition of mMate1-mediated efflux of type I organic cations in the liver and kidney by pyrimethamine

Sumito Ito, Hiroyuki Kusuhara, Yushun Kuroiwa, Chunyong Wu, Yoshinori Moriyama, Katsuhisa Inoue, Tsunenori Kondo, Hiroaki Yuasa, Hideki Nakayama, Shigeru Horita and Yuichi Sugiyama

Journal of Pharmacology and Experimental Therapeutics January 11, 2010, jpet.109.163642; DOI: https://doi.org/10.1124/jpet.109.163642

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Potent and specific inhibition of mMate1-mediated efflux of type I organic cations in the liver and kidney by pyrimethamine

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Potent and specific inhibition of mMate1-mediated efflux of type I organic cations in the liver and kidney by pyrimethamine

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