A Single Point Mutation (N514Y) in the Human M3 Muscarinic Acetylcholine Receptor Reveals Differences in the Properties of Antagonists: Evidence for Differential Inverse Agonism

Mark R. Dowling; Jonathon M. Willets; David C. Budd; Steven J. Charlton; Stefan R. Nahorski; R.A. John Challiss

doi:10.1124/jpet.106.101246

OtherCellular and Molecular

A Single Point Mutation (N514Y) in the Human M3 Muscarinic Acetylcholine Receptor Reveals Differences in the Properties of Antagonists: Evidence for Differential Inverse Agonism

Mark R. Dowling, Jonathon M. Willets, David C. Budd, Steven J. Charlton, Stefan R. Nahorski and R.A. John Challiss

Journal of Pharmacology and Experimental Therapeutics February 17, 2006, DOI: https://doi.org/10.1124/jpet.106.101246

Mark R. Dowling

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Jonathon M. Willets

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David C. Budd

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Steven J. Charlton

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Stefan R. Nahorski

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R.A. John Challiss

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Journal of Pharmacology and Experimental Therapeutics

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OtherCellular and Molecular

A Single Point Mutation (N514Y) in the Human M3 Muscarinic Acetylcholine Receptor Reveals Differences in the Properties of Antagonists: Evidence for Differential Inverse Agonism

Mark R. Dowling, Jonathon M. Willets, David C. Budd, Steven J. Charlton, Stefan R. Nahorski and R.A. John Challiss

Journal of Pharmacology and Experimental Therapeutics February 17, 2006, DOI: https://doi.org/10.1124/jpet.106.101246

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OtherCellular and Molecular

A Single Point Mutation (N514Y) in the Human M3 Muscarinic Acetylcholine Receptor Reveals Differences in the Properties of Antagonists: Evidence for Differential Inverse Agonism

Mark R. Dowling, Jonathon M. Willets, David C. Budd, Steven J. Charlton, Stefan R. Nahorski and R.A. John Challiss

Journal of Pharmacology and Experimental Therapeutics February 17, 2006, DOI: https://doi.org/10.1124/jpet.106.101246

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A Single Point Mutation (N514Y) in the Human M3 Muscarinic Acetylcholine Receptor Reveals Differences in the Properties of Antagonists: Evidence for Differential Inverse Agonism

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A Single Point Mutation (N514Y) in the Human M3 Muscarinic Acetylcholine Receptor Reveals Differences in the Properties of Antagonists: Evidence for Differential Inverse Agonism

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