More articles from Toxicology

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Different Mechanisms for Histone Acetylation by Ethanol and Its Metabolite Acetate in Rat Primary Hepatocytes
Shivendra D. Shukla, Ricardo Restrepo, Philip Fish, Robert W. Lim and Jamal A. Ibdah

Journal of Pharmacology and Experimental Therapeutics July 2015, 354 (1) 18-23; DOI: https://doi.org/10.1124/jpet.115.223867
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Sulfa Drugs Inhibit Sepiapterin Reduction and Chemical Redox Cycling by Sepiapterin Reductase
Shaojun Yang, Yi-Hua Jan, Vladimir Mishin, Jason R. Richardson, Muhammad M. Hossain, Ned D. Heindel, Diane E. Heck, Debra L. Laskin and Jeffrey D. Laskin

Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 529-540; DOI: https://doi.org/10.1124/jpet.114.221572
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Multiple Compound-Related Adverse Properties Contribute to Liver Injury Caused by Endothelin Receptor Antagonists
J. Gerry Kenna, Simone H. Stahl, Julie A. Eakins, Alison J. Foster, Linda C. Andersson, Jonas Bergare, Martin Billger, Marie Elebring, Charles S. Elmore and Richard A. Thompson

Journal of Pharmacology and Experimental Therapeutics February 2015, 352 (2) 281-290; DOI: https://doi.org/10.1124/jpet.114.220491
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Chimeric TK-NOG Mice: A Predictive Model for Cholestatic Human Liver Toxicity
Dan Xu, Manhong Wu, Sachiko Nishimura, Toshihiko Nishimura, Sara A. Michie, Ming Zheng, Zicheng Yang, Alexander John Yates, Jeffrey S. Day, Kathleen M. Hillgren, Saori Takedai Takeda, Yuan Guan, Yingying Guo and Gary Peltz

Journal of Pharmacology and Experimental Therapeutics February 2015, 352 (2) 274-280; DOI: https://doi.org/10.1124/jpet.114.220798
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Mechanistic Understanding for the Greater Sensitivity of Monkeys to Antisense Oligonucleotide–Mediated Complement Activation Compared with Humans
Lijiang Shen, Ashley Frazer-Abel, Paul R. Reynolds, Patricia C. Giclas, Alfred Chappell, Michael K. Pangburn, Husam Younis and Scott P. Henry

Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 709-717; DOI: https://doi.org/10.1124/jpet.114.219378
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Gambierol Inhibition of Voltage-Gated Potassium Channels Augments Spontaneous Ca²⁺ Oscillations in Cerebrocortical Neurons
Zhengyu Cao, Yanjun Cui, Eric Busse, Suneet Mehrotra, Jon D. Rainier and Thomas F. Murray

Journal of Pharmacology and Experimental Therapeutics September 2014, 350 (3) 615-623; DOI: https://doi.org/10.1124/jpet.114.215319
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Mass Spectrometric Characterization of Circulating Covalent Protein Adducts Derived from a Drug Acyl Glucuronide Metabolite: Multiple Albumin Adductions in Diclofenac Patients
Thomas G. Hammond, Xiaoli Meng, Rosalind E. Jenkins, James L. Maggs, Anahi Santoyo Castelazo, Sophie L. Regan, Stuart N. L. Bennett, Caroline J. Earnshaw, Guruprasad P. Aithal, Ira Pande, J. Gerry Kenna, Andrew V. Stachulski, B. Kevin Park and Dominic P. Williams

Journal of Pharmacology and Experimental Therapeutics August 2014, 350 (2) 387-402; DOI: https://doi.org/10.1124/jpet.114.215079
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Trovafloxacin Enhances Lipopolysaccharide-Stimulated Production of Tumor Necrosis Factor-α by Macrophages: Role of the DNA Damage Response
Kyle L. Poulsen, Jesus Olivero-Verbel, Kevin M. Beggs, Patricia E. Ganey and Robert A. Roth

Journal of Pharmacology and Experimental Therapeutics July 2014, 350 (1) 164-170; DOI: https://doi.org/10.1124/jpet.114.214189
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Macitentan Does Not Interfere with Hepatic Bile Salt Transport
Alexander Treiber, Päivi Äänismaa, Ruben de Kanter, Stephane Delahaye, Marianne Treher, Patrick Hess and Patricia Sidharta

Journal of Pharmacology and Experimental Therapeutics July 2014, 350 (1) 130-143; DOI: https://doi.org/10.1124/jpet.114.214106
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Trovafloxacin Potentiation of Lipopolysaccharide-Induced Tumor Necrosis Factor Release from RAW 264.7 Cells Requires Extracellular Signal-Regulated Kinase and c-Jun N-Terminal Kinase
Kyle L. Poulsen, Ryan P. Albee, Patricia E. Ganey and Robert A. Roth

Journal of Pharmacology and Experimental Therapeutics May 2014, 349 (2) 185-191; DOI: https://doi.org/10.1124/jpet.113.211276

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