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5-HT_2A Receptor Agonist-Induced Hyperthermia Is Induced via Vasoconstriction by Peripheral 5-HT_2A Receptors and Brown Adipose Tissue Thermogenesis by Peripheral Serotonin Loss at a High Ambient Temperature
Mami Nakamura, Kaori Shintani-Ishida and Hiroshi Ikegaya

Journal of Pharmacology and Experimental Therapeutics November 2018, 367 (2) 356-362; DOI: https://doi.org/10.1124/jpet.118.250217
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Low Concentrations of Arsenite Target the Intraluminal Inositol 1, 4, 5-Trisphosphate Receptor/Ryanodine Receptor Crosstalk to Significantly Elevate Intracellular Ca²⁺
Andrea Guidarelli, Mara Fiorani and Orazio Cantoni

Journal of Pharmacology and Experimental Therapeutics October 2018, 367 (1) 184-193; DOI: https://doi.org/10.1124/jpet.118.250480
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NOX4 Deletion in Male Mice Exacerbates the Effect of Ethanol on Trabecular Bone and Osteoblastogenesis
James Watt, Alexander W. Alund, Casey F. Pulliam, Kelly E. Mercer, Larry J. Suva, Jin-Ran Chen and Martin J. J. Ronis

Journal of Pharmacology and Experimental Therapeutics July 2018, 366 (1) 46-57; DOI: https://doi.org/10.1124/jpet.117.247262
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3,4-Dihydroxyphenylacetaldehyde-Induced Protein Modifications and Their Mitigation by N-Acetylcysteine
Yunden Jinsmaa, Yehonatan Sharabi, Patti Sullivan, Risa Isonaka and David S. Goldstein

Journal of Pharmacology and Experimental Therapeutics July 2018, 366 (1) 113-124; DOI: https://doi.org/10.1124/jpet.118.248492
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Drug-Induced Alterations of Mitochondrial DNA Homeostasis in Steatotic and Nonsteatotic HepaRG Cells
Dounia Le Guillou, Simon Bucher, Karima Begriche, Delphine Hoët, Anne Lombès, Gilles Labbe and Bernard Fromenty

Journal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 711-726; DOI: https://doi.org/10.1124/jpet.117.246751
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A Model Mechanism-Based Explanation of an In Vitro-In Vivo Disconnect for Improving Extrapolation and Translation
Andrew K. Smith, Yanli Xu, Glen E. P. Ropella and C. Anthony Hunt

Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 127-138; DOI: https://doi.org/10.1124/jpet.117.245019
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Effect of Ibuprofen on Skeletal Muscle of Dysferlin-Null Mice
Alyssa F. Collier, Jessica Gumerson, Kimmo Lehtimäki, Jukka Puoliväli, Jace W. Jones, Maureen A. Kane, Sankeerth Manne, Andrea O’Neill, Hillarie P. Windish, Toni Ahtoniemi, Bradley A. Williams, Douglas E. Albrecht and Robert J. Bloch

Journal of Pharmacology and Experimental Therapeutics March 2018, 364 (3) 409-419; DOI: https://doi.org/10.1124/jpet.117.244244
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Urolithin A Mitigates Cisplatin-Induced Nephrotoxicity by Inhibiting Renal Inflammation and Apoptosis in an Experimental Rat Model
Melissa Guada, Raghu Ganugula, Manicka Vadhanam and Majeti N.V. Ravi Kumar

Journal of Pharmacology and Experimental Therapeutics October 2017, 363 (1) 58-65; DOI: https://doi.org/10.1124/jpet.117.242420
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Synergistic Cytotoxicity from Drugs and Cytokines In Vitro as an Approach to Classify Drugs According to Their Potential to Cause Idiosyncratic Hepatotoxicity: A Proof-of-Concept Study
Ashley R. Maiuri, Bronlyn Wassink, Jonathan D. Turkus, Anna B. Breier, Theresa Lansdell, Gurpreet Kaur, Sarah L. Hession, Patricia E. Ganey and Robert A. Roth

Journal of Pharmacology and Experimental Therapeutics September 2017, 362 (3) 459-473; DOI: https://doi.org/10.1124/jpet.117.242354
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Dieldrin Augments mTOR Signaling and Regulates Genes Associated with Cardiovascular Disease in the Adult Zebrafish Heart (Danio rerio)
Logan Slade, Andrew Cowie, Chris J. Martyniuk, Petra C. Kienesberger and Thomas Pulinilkunnil

Journal of Pharmacology and Experimental Therapeutics June 2017, 361 (3) 375-385; DOI: https://doi.org/10.1124/jpet.116.239806

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