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Association between N-desmethylclozapine and clozapine-induced sialorrhea: Involvement of increased nocturnal salivary secretion via muscarinic receptors by N-desmethylclozapine
Shuhei Ishikawa, Masaki Kobayashi, Naoki Hashimoto, Hideaki Mikami, Akihiko Tanimura, Katsuya Narumi, Ayako Furugen, Ichiro Kusumi and Ken Iseki

Journal of Pharmacology and Experimental Therapeutics August 29, 2020, JPET-AR-2020-000164; DOI: https://doi.org/10.1124/jpet.120.000164
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A Novel Potent and Selective Histamine H3 Receptor Antagonist Enerisant: In Vitro Profiles, In Vivo Receptor Occupancy, Wake-Promoting and Pro-cognitive Effects in Rodents
Noriko Hino, Toshiyuki Marumo, Makiko Kotani, Toshiharu Shimazaki, Ayaka Kaku-Fukumoto, Hirohiko Hikichi, Jun-ichi Karasawa, Yasumitsu Tomishima, Hiroko Komiyama, Emi Tatsuda, Dai Nozawa, Toshio Nakamura and Shigeyuki Chaki

Journal of Pharmacology and Experimental Therapeutics August 29, 2020, JPET-AR-2020-000185; DOI: https://doi.org/10.1124/jpet.120.000185
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Fentanyl but not Morphine Interacts with Nonopioid Recombinant Human Neurotransmitter Receptors and Transporters
Randy Torralva, Amy J. Eshleman, Tracy L. Swanson, Jennifer L. Schmachtenberg, William E. Schutzer, Shelley H. Bloom, Katherine M. Wolfrum, John F. Reed and Aaron Janowsky

Journal of Pharmacology and Experimental Therapeutics September 2020, 374 (3) 376-391; DOI: https://doi.org/10.1124/jpet.120.265561
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Chronic Morphine-Induced Changes in Signaling at the A₃ Adenosine Receptor Contribute to Morphine-Induced Hyperalgesia, Tolerance, and Withdrawal
Timothy M. Doyle, Tally M. Largent-Milnes, Zhoumou Chen, Vasiliki Staikopoulos, Emanuela Esposito, Rebecca Dalgarno, Churmy Fan, Dilip K. Tosh, Salvatore Cuzzocrea, Kenneth A. Jacobson, Tuan Trang, Mark R. Hutchinson, Gary J. Bennett, Todd W. Vanderah and Daniela Salvemini

Journal of Pharmacology and Experimental Therapeutics August 2020, 374 (2) 331-341; DOI: https://doi.org/10.1124/jpet.120.000004
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3,4-Methylenedioxypyrovalerone: Neuropharmacological Impact of a Designer Stimulant of Abuse on Monoamine Transporters
Charlotte P. Magee, Christopher L. German, Yasmeen H. Siripathane, Peter S. Curtis, David J. Anderson, Diana G. Wilkins, Glen R. Hanson and Annette E. Fleckenstein

Journal of Pharmacology and Experimental Therapeutics August 2020, 374 (2) 273-282; DOI: https://doi.org/10.1124/jpet.119.264895
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[³H]Dopamine Uptake through the Dopamine and Norepinephrine Transporters is Decreased in the Prefrontal Cortex of Transgenic Mice Expressing HIV-1 Transactivator of Transcription Protein
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Journal of Pharmacology and Experimental Therapeutics August 2020, 374 (2) 241-251; DOI: https://doi.org/10.1124/jpet.120.266023
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MK-8719, a Novel and Selective O-GlcNAcase Inhibitor That Reduces the Formation of Pathological Tau and Ameliorates Neurodegeneration in a Mouse Model of Tauopathy
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Journal of Pharmacology and Experimental Therapeutics August 2020, 374 (2) 252-263; DOI: https://doi.org/10.1124/jpet.120.266122
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Comparative Pharmacokinetics of Δ⁹-Tetrahydrocannabinol in Adolescent and Adult Male Mice
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Journal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 151-160; DOI: https://doi.org/10.1124/jpet.120.265892
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Effects of a Novel Psychomotor Stabilizer, IRL790, on Biochemical Measures of Synaptic Markers and Neurotransmission
Kristina Becanovic, Maria Vittoria de Donno, Vasco C. Sousa, Joakim Tedroff and Per Svenningsson

Journal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 126-133; DOI: https://doi.org/10.1124/jpet.119.264754
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Use of a Noninvasive Brain-Penetrating Peptide-Drug Conjugate Strategy to Improve the Delivery of Opioid Pain Relief Medications to the Brain
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Journal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 52-61; DOI: https://doi.org/10.1124/jpet.119.263566

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