More articles from Metabolism, Transport, and Pharmacogenetics

You have access
Novel Bile Acid-Dependent Mechanisms of Hepatotoxicity Associated with Tyrosine Kinase Inhibitors
Chitra Saran, Louise Sundqvist, Henry Ho, Jonna Niskanen, Paavo Honkakoski and Kim L. R. Brouwer

Journal of Pharmacology and Experimental Therapeutics February 2022, 380 (2) 114-125; DOI: https://doi.org/10.1124/jpet.121.000828
You have access
Central Nervous System Distribution of an Opioid Agonist Combination with Synergistic Activity
Jessica I. Griffith, Minjee Kim, Daniel J. Bruce, Cristina D. Peterson, Kelley F. Kitto, Afroz S. Mohammad, Sneha Rathi, Carolyn A. Fairbanks, George L. Wilcox and William F. Elmquist

Journal of Pharmacology and Experimental Therapeutics January 2022, 380 (1) 34-46; DOI: https://doi.org/10.1124/jpet.121.000821
You have access
Differential Susceptibilities of Catecholamines to Metabolism by Monoamine Oxidases
David S. Goldstein, Genessis Castillo, Patti Sullivan and Yehonatan Sharabi

Journal of Pharmacology and Experimental Therapeutics November 2021, 379 (3) 253-259; DOI: https://doi.org/10.1124/jpet.121.000826
You have access
Cationic Compounds with SARS-CoV-2 Antiviral Activity and Their Interaction with Organic Cation Transporter/Multidrug and Toxin Extruder Secretory Transporters
Lucy Martinez-Guerrero, Xiaohong Zhang, Kimberley M. Zorn, Sean Ekins and Stephen H. Wright

Journal of Pharmacology and Experimental Therapeutics October 2021, 379 (1) 96-107; DOI: https://doi.org/10.1124/jpet.121.000619
You have access
Protein Kinase N Family Negatively Regulates Constitutive Androstane Receptor-Mediated Transcriptional Induction of Cytochrome P450 2b10 in the Livers of Mice
Atsushi Kawase, Hideyuki Mukai, Shunsuke Tateishi, Shintaro Kuroda, Akira Kazaoka, Ryosuke Satoh, Hiroaki Shimada, Reiko Sugiura and Masahiro Iwaki

Journal of Pharmacology and Experimental Therapeutics October 2021, 379 (1) 53-63; DOI: https://doi.org/10.1124/jpet.121.000790
You have access
Enhancing Target Tissue Levels and Diminishing Plasma Clearance of Ionizing Zwitterionic Antidotes in Organophosphate Exposures
Yan-Jye Shyong, Yadira Sepulveda, Arnold Garcia, Nathan M. Samskey, Zoran Radic, Rakesh K. Sit, K. Barry Sharpless, Jeremiah D. Momper and Palmer Taylor

Journal of Pharmacology and Experimental Therapeutics September 2021, 378 (3) 315-321; DOI: https://doi.org/10.1124/jpet.121.000715
Open Access
Evaluation of Ipatasertib Interactions with Itraconazole and Coproporphyrin I and III in a Single Drug Interaction Study in Healthy Subjects
Rucha S. Sane, Kit Wun Kathy Cheung, Eunpi Cho, Bianca M. Liederer, Justin Hanover, Vikram Malhi, Emile Plise, Susan Wong and Luna Musib

Journal of Pharmacology and Experimental Therapeutics August 2021, 378 (2) 87-95; DOI: https://doi.org/10.1124/jpet.121.000620
Open Access
In Vitro Assessment of the Drug–Drug Interaction Potential of Verinurad and Its Metabolites as Substrates and Inhibitors of Metabolizing Enzymes and Drug Transporters
V. Sashi Gopaul, Anna Vildhede, Tommy B. Andersson, Fredrik Erlandsson, Caroline A. Lee, Susanne Johansson and Constanze Hilgendorf

Journal of Pharmacology and Experimental Therapeutics August 2021, 378 (2) 108-123; DOI: https://doi.org/10.1124/jpet.121.000549
You have access
γ-Hydroxybutyric Acid–Ethanol Drug-Drug Interaction: Reversal of Toxicity with Monocarboxylate Transporter 1 Inhibitors
Vivian Rodriguez-Cruz and Marilyn E. Morris

Journal of Pharmacology and Experimental Therapeutics July 2021, 378 (1) 42-50; DOI: https://doi.org/10.1124/jpet.121.000566
You have access
Organic Anion–Transporting Polypeptide 1B1/1B3–Mediated Hepatic Uptake Determines the Pharmacokinetics of Large Lipophilic Acids: In Vitro–In Vivo Evaluation in Cynomolgus Monkey
Heather Eng, Yi-an Bi, Mark A. West, Sangwoo Ryu, Emi Yamaguchi, Rachel E. Kosa, David A. Tess, David A. Griffith, John Litchfield, Amit S. Kalgutkar and Manthena V. S. Varma

Journal of Pharmacology and Experimental Therapeutics April 2021, 377 (1) 169-180; DOI: https://doi.org/10.1124/jpet.120.000457

Main menu

User menu

Search

More articles from Metabolism, Transport, and Pharmacogenetics

Pages

Navigate

More Information

ASPET's Other Journals