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Effects of Tegoprazan, a Novel Potassium-Competitive Acid Blocker, on Rat Models of Gastric Acid–Related Disease
Dong Kyu Kim, Keun-Ho Lee, Sung-jun Kim, Soo-Jin Kim, Song Jin Lee, Chi Hye Park, Bong-Tae Kim, Geun-Seog Song, Byoung-Seok Moon and Shin-Young Ryu

Journal of Pharmacology and Experimental Therapeutics June 2019, 369 (3) 318-327; DOI: https://doi.org/10.1124/jpet.118.254904
Open Access
Relationship between Pharmacokinetics and Pharmacodynamic Responses in Healthy Smokers Informs a Once-Daily Dosing Regimen for Nemiralisib
M. Begg, R. Wilson, J.N. Hamblin, M. Montembault, J. Green, A. Deans, A. Amour, S. Worsley, K. Fantom, Y. Cui, G. Dear, S. Ahmad, A. Kielkowska, J. Clark, M. Boyce, A. Cahn and E.M. Hessel

Journal of Pharmacology and Experimental Therapeutics June 2019, 369 (3) 337-344; DOI: https://doi.org/10.1124/jpet.118.255109
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Beneficial Metabolic Effects of Mirabegron In Vitro and in High-Fat Diet-Induced Obese Mice
Lei Hao, Sheyenne Scott, Mehrnaz Abbasi, Yujiao Zu, Md Shahjalal Hossain Khan, Yang Yang, Dayong Wu, Ling Zhao and Shu Wang

Journal of Pharmacology and Experimental Therapeutics June 2019, 369 (3) 419-427; DOI: https://doi.org/10.1124/jpet.118.255778
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Beneficial Effects of Trehalose on Striatal Dopaminergic Deficits in Rodent and Primate Models of Synucleinopathy in Parkinson’s Disease
Patrick A. Howson, Tom H. Johnston, Paula Ravenscroft, Michael P. Hill, Jin Su, Jonathan M. Brotchie and James B. Koprich

Journal of Pharmacology and Experimental Therapeutics June 2019, 369 (3) 364-374; DOI: https://doi.org/10.1124/jpet.118.255695
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Modulation of TARP γ8–Containing AMPA Receptors as a Novel Therapeutic Approach for Chronic Pain
Kelly L. Knopp, Rosa Maria A. Simmons, Wenhong Guo, Benjamin L. Adams, Kevin M. Gardinier, Douglas L. Gernert, Paul L. Ornstein, Warren Porter, Jon Reel, Chunjin Ding, He Wang, Yuewei Qian, Kevin D. Burris, Anne Need, Vanessa Barth, Steven Swanson, John Catlow, Jeffrey M. Witkin, Ruud Zwart, Emanuele Sher, Kar-Chan Choong, Theron M. Wall, Douglas Schober, Christian C. Felder, Akihiko S. Kato, David S. Bredt and Eric S. Nisenbaum

Journal of Pharmacology and Experimental Therapeutics June 2019, 369 (3) 345-363; DOI: https://doi.org/10.1124/jpet.118.250126
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Acetylcholine Inhibits Platelet Activation
John A. Bennett, Sara K. Ture, Rachel A. Schmidt, Michael A. Mastrangelo, Scott J. Cameron, Lara E. Terry, David I. Yule, Craig N. Morrell and Charles J. Lowenstein

Journal of Pharmacology and Experimental Therapeutics May 2019, 369 (2) 182-187; DOI: https://doi.org/10.1124/jpet.118.253583
Open Access
Pharmacological Characterization of a Novel 5-Hydroxybenzothiazolone-Derived β₂-Adrenoceptor Agonist with Functional Selectivity for Anabolic Effects on Skeletal Muscle Resulting in a Wider Cardiovascular Safety Window in Preclinical Studies
Magdalena Koziczak-Holbro, Dean F. Rigel, Bérengère Dumotier, David A. Sykes, Jeffrey Tsao, Ngoc-Hong Nguyen, Julian Bösch, Marie Jourdain, Ludivine Flotte, Yuichiro Adachi, Michael Kiffe, Moïse Azria, Robin A. Fairhurst, Steven J. Charlton, Brian P. Richardson, Estelle Lach-Trifilieff, David J. Glass, Thomas Ullrich and Shinji Hatakeyama

Journal of Pharmacology and Experimental Therapeutics May 2019, 369 (2) 188-199; DOI: https://doi.org/10.1124/jpet.118.255307
Open Access
Squalene-Adenosine Nanoparticles: Ligands of Adenosine Receptors or Adenosine Prodrug?
Marie Rouquette, Sinda Lepetre-Mouelhi, Ophélie Dufrançais, Xue Yang, Julie Mougin, Grégory Pieters, Sébastien Garcia-Argote, Adriaan P. IJzerman and Patrick Couvreur

Journal of Pharmacology and Experimental Therapeutics April 2019, 369 (1) 144-151; DOI: https://doi.org/10.1124/jpet.118.254961
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Ferroptosis as a Novel Therapeutic Target for Friedreich’s Ataxia
M. Grazia Cotticelli, Shujuan Xia, Daniel Lin, Taehee Lee, Leila Terrab, Peter Wipf, Donna M. Huryn and Robert B. Wilson

Journal of Pharmacology and Experimental Therapeutics April 2019, 369 (1) 47-54; DOI: https://doi.org/10.1124/jpet.118.252759
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A Novel Angiotensin-(1-7) Glycosylated Mas Receptor Agonist for Treating Vascular Cognitive Impairment and Inflammation-Related Memory Dysfunction
Meredith Hay, Robin Polt, Michael L. Heien, Todd W. Vanderah, Tally M. Largent-Milnes, Kathleen Rodgers, Torsten Falk, Mitchell J. Bartlett, Kristian P. Doyle and John P. Konhilas

Journal of Pharmacology and Experimental Therapeutics April 2019, 369 (1) 9-25; DOI: https://doi.org/10.1124/jpet.118.254854

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