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Mechanistic analysis of an ERK2-interacting compound that inhibits mutant-BRAF expressing melanoma cells by inducing oxidative stress
Ramon Martinez, Weiliang Huang, Ramin Samadani, Bryan Mackowiak, Garrick Centola, Lijia Chen, Ivie L Conlon, Kellie Hom, Maureen A. Kane, Steven Fletcher and Paul Shapiro

Journal of Pharmacology and Experimental Therapeutics October 27, 2020, JPET-AR-2020-000266; DOI: https://doi.org/10.1124/jpet.120.000266
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Effects of Topical Application of CHF6467, a Mutated Form of Human Nerve Growth Factor, on Skin Wound Healing in Diabetic Mice
A. Giuliani, L. Lorenzini, V.A. Baldassarro, M. Pannella, M. Cescatti, M. Fernandez, G. Alastra, A. Flagelli, G. Villetti, B.P. Imbimbo, L. Giardino and L. Calzà

Journal of Pharmacology and Experimental Therapeutics November 2020, 375 (2) 317-331; DOI: https://doi.org/10.1124/jpet.120.000110
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Angiotensin-(1–7) Rescues Chronic Intermittent Hypoxia-Aggravated Transforming Growth Factor-β–Mediated Airway Remodeling in Murine and Cellular Models of Asthma
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Journal of Pharmacology and Experimental Therapeutics November 2020, 375 (2) 268-275; DOI: https://doi.org/10.1124/jpet.120.000150
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Celastrol Dilates and Counteracts Ethanol-Induced Constriction of Cerebral Arteries
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Journal of Pharmacology and Experimental Therapeutics November 2020, 375 (2) 247-257; DOI: https://doi.org/10.1124/jpet.120.000152
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Mechanism of Action of Veverimer: A Novel, Orally Administered, Non-absorbed, Counterion-Free, Hydrochloric Acid Binder under Development for the Treatment of Metabolic Acidosis in Chronic Kidney Disease
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Journal of Pharmacology and Experimental Therapeutics October 8, 2020, JPET-AR-2020-000190; DOI: https://doi.org/10.1124/jpet.120.000190
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Activation of naturally occurring LCAT mutants by a novel activator compound
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Journal of Pharmacology and Experimental Therapeutics September 26, 2020, JPET-AR-2020-000159; DOI: https://doi.org/10.1124/jpet.120.000159
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Monoclonal antibodies counteract opioid-induced behavioral and toxic effects in mice and rats
Carly Anne Baehr, April Huseby Kelcher, Aaron Khaimraj, Dana E Reed, Sujata G Pandit, David AuCoin, Saadyah Averick and Marco Pravetoni

Journal of Pharmacology and Experimental Therapeutics September 26, 2020, JPET-AR-2020-000124; DOI: https://doi.org/10.1124/jpet.120.000124
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Semi-Mechanistic Pharmacokinetic Modeling of Lipid Core Nanocapsules: Understanding Quetiapine Plasma and Brain Disposition in a Neurodevelopmental Animal Model of Schizophrenia
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Delayed Adjunctive Treatment of Organophosphate-Induced Status Epilepticus in Rats with Phenobarbital, Memantine, or Dexmedetomidine
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GPR183-oxysterol axis in spinal cord contributes to neuropathic pain
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Journal of Pharmacology and Experimental Therapeutics September 10, 2020, JPET-AR-2020-000105; DOI: https://doi.org/10.1124/jpet.120.000105

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