Abstract
1. Demerol is hydrolyzed by the livers of various animals but not by any of the other tissues tested.
2. The hydrolysis is inhibited by eserine and by fluoride.
3. The enzyme responsible for the hydrolysis is distinct from the tropine esterases, cholinesterases, and the esterases which hydrolyze aliphatic esters.
Footnotes
- Received June 11, 1945.
JPET articles become freely available 12 months after publication, and remain freely available for 5 years.Non-open access articles that fall outside this five year window are available only to institutional subscribers and current ASPET members, or through the article purchase feature at the bottom of the page.
|
Log in using your username and password
Purchase access
You may purchase access to this article. This will require you to create an account if you don't already have one.