Abstract
On the basis of equal oral dosage sulfacetimide produced higher survival rates than sulfanilamide in mice experimentally infected with Escherichia coli. However, since the blood concentration-time curves obtained with the dosage schedule employed may be dissimilar for the two drugs, it cannot be presumed from these experiments that sulfacetimide is more active therapeutically than sulfanilamide in this infection.
Footnotes
- Received July 7, 1941.
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THE THERAPEUTIC EFFECT OF SULFACETIMIDE IN EXPERIMENTAL INFECTIONS DUE TO ESCHERICHIA COLI
