Abstract
The effect of sodium nitrite, potassium thiocyanate, erythrol tetranitrate, Allium sativum, acetyl-β-methylcholine, sodium chloride, and renal extract on the blood pressures of hypertensive rats was investigated. The blood pressure was reduced to normal levels following the administration of renal extract. None of the so-called "depressor" or "hypotensive" substances manifested an ability to reduce appreciably the blood pressure and their clinical value is thus questionable. The administration of a relatively large dose of sodium chloride did not markedly elevate the blood pressure.
Footnotes
- Received February 28, 1940.
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