Abstract
The distribution of barbital in the different parts of the central nervous system is the same after large, i.e. anesthetic (225 to 600 mgm. per kilogram) and after small, i.e., hypnotic doses (50 to 100 mgm. per kilogram).
Keeser and Keeser's claim of specific distribution of barbital and its accumulation in the so-called sleep centers after the administration of small hypnotic doses could not be confirmed.
Footnotes
- Received February 27, 1935.
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