Abstract
1. The clinical features of acute and chronic acetanilid poisoning have been reviewed briefly.
2. In experiments on two dogs the first effect of daily acetanilid ingestion was an anemia. Following prolonged administration the animals gained tolerance. After ingestion of acetanilid there was a transient methemoglobinemia and increase in blood phenol. During methemoglobinemia oxygen capacity falls and symptoms of anoxemia may result. No cardiac damage was demonstrable by electrocardiograms. Acetanilid is habit forming.
Footnotes
- Received January 2, 1935.
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