Abstract
1. Ephedrine is mainly stimulant to the excised ureter of the dog and the pig (Sus scrofa domestica).
2. Depression of the excised ureter occurs after the use of large doses of ephedrine, the depression invariably following a rather extended period of stimulation.
3. The qualitative effect of ephedrine on the excised ureter resembles that produced by epinephrine, except that after large doses of ephedrine depression is secondarily produced.
4. Epinephrine is 1 to 200 times as actively stimulant as ephedrine.
Footnotes
- Received April 19, 1930.
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